Biological applications of LbL multilayer capsules: From drug delivery to sensing

LL Del Mercato, MM Ferraro, F Baldassarre… - Advances in colloid and …, 2014 - Elsevier
Polyelectrolyte multilayer (PEM) capsules engineered with active elements for targeting,
labeling, sensing and delivery hold great promise for the controlled delivery of drugs and the …

The rationale for targeting TGF‐β in chronic liver diseases

G Giannelli, W Mikulits, S Dooley… - European Journal of …, 2016 - Wiley Online Library
Background Transforming growth factor (TGF)‐β is a pluripotent cytokine that displays
several tissue‐specific biological activities. In the liver, TGF‐β is considered a fundamental …

Intracellularly biodegradable polyelectrolyte/silica composite microcapsules as carriers for small molecules

H Gao, OA Goriacheva, NV Tarakina… - … applied materials & …, 2016 - ACS Publications
Microcapsules that can be efficiently loaded with small molecules and effectively released at
the target area through the degradation of the capsule shells hold great potential for treating …

Enhanced Bioactivity of Pomegranate Peel Extract following Controlled Release from CaCO3 Nanocrystals

F Baldassarre, V Vergaro, F De Castro… - Bioinorganic …, 2022 - Wiley Online Library
Pomegranate peel extract is rich of interesting bioactive chemicals, principally phenolic
compounds, which have shown antimicrobial, anticancer, and antioxidative properties. The …

Cubical shape enhances the interaction of layer‐by‐layer polymeric particles with breast cancer cells

JF Alexander, V Kozlovskaya, J Chen… - Advanced …, 2015 - Wiley Online Library
Blood‐borne objects display a nonspherical shape with in‐flow dimensions much larger
than the vascular endothelial fenestrations, yet, at the diseased state, are able to traverse …

A facile and efficient strategy to encapsulate the model basic protein lysozyme into porous CaCO 3

P Shi, S Luo, B Voit, D Appelhans, X Zan - Journal of Materials …, 2018 - pubs.rsc.org
Basic proteins play important roles in biological activities and disease treatment, but their
high sensitivity to the body environment and short life time have limited their applications …

Nanomedicine-mediated alteration of the pharmacokinetic profile of small molecule cancer immunotherapeutics

S Van Herck, BG De Geest - Acta Pharmacologica Sinica, 2020 - nature.com
The advent of immunotherapy is a game changer in cancer therapy with monoclonal
antibody-and T cell-based therapeutics being the current flagships. Small molecule …

A predictive model of iron oxide nanoparticles flocculation tuning Z-potential in aqueous environment for biological application

F Baldassarre, M Cacciola, G Ciccarella - Journal of Nanoparticle …, 2015 - Springer
Iron oxide nanoparticles are the most used magnetic nanoparticles in biomedical and
biotechnological field because of their nontoxicity respect to the other metals. The …

Synthesis of biocompatible polymeric nano-capsules based on calcium carbonate: A potential cisplatin delivery system

V Vergaro, P Papadia, S Leporatti… - Journal of inorganic …, 2015 - Elsevier
A smart nanocarrier system for cancer therapy, based on a recently developed technique for
preparing pure nanometric calcium carbonate (CaCO 3), was studied. Different approaches …

The use of a barley-based well to define cationic betaglucan to study mammalian cell toxicity associated with interactions with biological structures

M Tymecka, K Hac-Wydro, M Obloza, P Bonarek… - Pharmaceutics, 2023 - mdpi.com
Among potential macromolecule-based pharmaceuticals, polycations seem particularly
interesting due to their proven antimicrobial properties and use as vectors in gene therapy …