Gastric cancer: a comprehensive review of current and future treatment strategies
RE Sexton, MN Al Hallak, M Diab, AS Azmi - Cancer and Metastasis …, 2020 - Springer
Gastric cancer remains a major unmet clinical problem with over 1 million new cases
worldwide. It is the fourth most commonly occurring cancer in men and the seventh most …
worldwide. It is the fourth most commonly occurring cancer in men and the seventh most …
Attacking the PI3K/Akt/mTOR signaling pathway for targeted therapeutic treatment in human cancer
Cancer is the second leading cause of human death globally. PI3K/Akt/mTOR signaling is
one of the most frequently dysregulated signaling pathways observed in cancer patients that …
one of the most frequently dysregulated signaling pathways observed in cancer patients that …
RETRACTED ARTICLE: Roles of the PI3K/AKT/mTOR signalling pathways in neurodegenerative diseases and tumours
F Xu, L Na, Y Li, L Chen - Cell & bioscience, 2020 - Springer
Abstract The PI3 K/AKT/mTOR signalling pathway plays an important role in the regulation of
signal transduction and biological processes such as cell proliferation, apoptosis …
signal transduction and biological processes such as cell proliferation, apoptosis …
mTOR signaling in cancer and mTOR inhibitors in solid tumor targeting therapy
T Tian, X Li, J Zhang - International journal of molecular sciences, 2019 - mdpi.com
The mammalian or mechanistic target of rapamycin (mTOR) pathway plays a crucial role in
regulation of cell survival, metabolism, growth and protein synthesis in response to upstream …
regulation of cell survival, metabolism, growth and protein synthesis in response to upstream …
Crosstalk between miRNA and PI3K/AKT/mTOR signaling pathway in cancer
M Akbarzadeh, A Mihanfar, S Akbarzadeh, B Yousefi… - Life Sciences, 2021 - Elsevier
Abstract Phosphoinositide-3 kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR)
signaling pathway is one of the most important proliferative signaling pathways with critical …
signaling pathway is one of the most important proliferative signaling pathways with critical …
A systematic review of the biological effects of cordycepin
M Radhi, S Ashraf, S Lawrence, AA Tranholm… - Molecules, 2021 - mdpi.com
We conducted a systematic review of the literature on the effects of cordycepin on cell
survival and proliferation, inflammation, signal transduction and animal models. A total of …
survival and proliferation, inflammation, signal transduction and animal models. A total of …
RIPK1-dependent necroptosis promotes vasculogenic mimicry formation via eIF4E in triple-negative breast cancer
F Li, H Sun, Y Yu, N Che, J Han, R Cheng… - Cell Death & …, 2023 - nature.com
Necroptosis is a caspase-independent form of programmed cell death. Receptor interacting
protein kinase 1 (RIPK1) is a key molecule in the initiation of necroptosis and the formation …
protein kinase 1 (RIPK1) is a key molecule in the initiation of necroptosis and the formation …
Long non-coding RNAs (lncRNAs) as regulators of the PI3K/AKT/mTOR pathway in gastric carcinoma
Gastric cancer (GC) represents~ 10% of the global cancer-related deaths, increasingly
affecting the younger population in active stages of life. The high mortality of GC is due to …
affecting the younger population in active stages of life. The high mortality of GC is due to …
Triphenylphosphonium conjugated gold nanotriangles impact Pi3K/AKT pathway in breast cancer cells: a photodynamic therapy approach
NM Vinita, U Devan, S Durgadevi, S Anitha… - Scientific Reports, 2023 - nature.com
Although gold nanoparticles based photodynamic therapy (PDT) were reported to improve
efficacy and specificity, the impact of surface charge in targeting cancer is still a challenge …
efficacy and specificity, the impact of surface charge in targeting cancer is still a challenge …
Alnustone inhibits the growth of hepatocellular carcinoma via ROS‐mediated PI3K/Akt/mTOR/p70S6K axis
L Wang, L Cheng, L Ma, A Ahmad Farooqi… - Phytotherapy …, 2022 - Wiley Online Library
Alnustone, a diarylheptane compound, exhibits potent growth inhibition against
hepatocellular carcinoma (HCC) BEL‐7402 cells. However, the underlying mechanisms …
hepatocellular carcinoma (HCC) BEL‐7402 cells. However, the underlying mechanisms …