NMD: a multifaceted response to premature translational termination

S Kervestin, A Jacobson - Nature reviews Molecular cell biology, 2012 - nature.com
Although most mRNA molecules derived from protein-coding genes are destined to be
translated into functional polypeptides, some are eliminated by cellular quality control …

RNA Degradation in Saccharomyces cerevisae

R Parker - Genetics, 2012 - academic.oup.com
All RNA species in yeast cells are subject to turnover. Work over the past 20 years has
defined degradation mechanisms for messenger RNAs, transfer RNAs, ribosomal RNAs …

Regulation of natural mRNAs by the nonsense-mediated mRNA decay pathway

M Peccarelli, BW Kebaara - Eukaryotic cell, 2014 - Am Soc Microbiol
The nonsense-mediated mRNA decay (NMD) pathway is a specialized mRNA degradation
pathway that degrades select mRNAs. This pathway is conserved in all eukaryotes …

The long and short of EJC-independent nonsense-mediated RNA decay

O Muñoz, M Lore, S Jagannathan - Biochemical Society …, 2023 - portlandpress.com
Nonsense-mediated RNA decay (NMD) plays a dual role as an RNA surveillance
mechanism against aberrant transcripts containing premature termination codons and as a …

Global deletome profile of Saccharomyces cerevisiae exposed to lithium

N Fierling, P Billard, P Bauda, D Blaudez - Metallomics, 2024 - academic.oup.com
The increasing use of lithium (Li) in new technologies raises the question of its impact on
living microorganisms. In the present study, we aimed to identify putative Li targets and …

The nonsense-mediated mRNA decay (NMD) pathway differentially regulates COX17, COX19 and COX23 mRNAs

K Murtha, M Hwang, MC Peccarelli, TD Scott… - Current genetics, 2019 - Springer
The differential regulation of COX17, COX19 and COX23 mRNAs by the nonsense-
mediated mRNA decay (NMD) pathway was investigated. The NMD pathway regulates …

Nonsense-mediated mRNA decay and metal ion homeostasis and detoxification in Saccharomyces cerevisiae

X Zhang, BW Kebaara - Biometals, 2022 - Springer
The highly conserved Nonsense-mediated mRNA decay (NMD) pathway is a translation
dependent mRNA degradation pathway. Although NMD is best known for its role in …

mRNA quality control pathways in Saccharomyces cerevisiae

S Das, B Das - Journal of biosciences, 2013 - Springer
Efficient production of translation-competent mRNAs involves processing and modification
events both in the nucleus and cytoplasm which require a number of complex machineries …

mRNAs involved in copper homeostasis are regulated by the nonsense-mediated mRNA decay pathway depending on environmental conditions

M Peccarelli, TD Scott, M Steele… - Fungal Genetics and …, 2016 - Elsevier
The nonsense-mediated mRNA decay pathway (NMD) is an mRNA degradation pathway
that degrades mRNAs that prematurely terminate translation. These mRNAs include mRNAs …

Nonsense-mediated mRNA decay of metal-binding activator MAC1 is dependent on copper levels and 3′-UTR length in Saccharomyces cerevisiae

X Zhang, BW Kebaara - Current Genetics, 2024 - Springer
The nonsense-mediated mRNA decay (NMD) pathway was initially identified as a
surveillance pathway that degrades mRNAs containing premature termination codons …