Successful behavior requires actively acquiring and representing information about the
environment and people, and manipulating and using those acquired representations …

The hippocampal formation has been implicated in a growing number of disorders, from
Alzheimer's disease and cognitive ageing to schizophrenia and depression. How can the …

Context Although differences in clinical characteristics exist between major depressive
disorder (MDD) and bipolar disorder (BD), consistent structural brain abnormalities that …

Major depressive disorder (MDD) has until recently been conceptualized as an episodic
disorder associated with 'chemical imbalances' but no permanent brain changes. Evidence …

Objective. So far, there have been no attempts to integrate the growing number of all brain
volumetric magnetic resonance imaging studies in depression. In this comprehensive meta …

Previous meta-analyses of structural MRI studies have shown diffuse cortical and sub-
cortical abnormalities in unipolar depression. However, the presence of duplicate …

OBJECTIVE: Several studies have found reduced hippocampal volume in patients with
unipolar depression, but discrepancies exist. The authors performed a systematic review …

Background: Some, although not all, studies report small hippocampal volume in patients
with major depressive disorder (MDD) relative to healthy controls. Here, we explore the …

OBJECTIVE: A number of studies have used magnetic resonance imaging to examine
volumetric differences in temporal structures in subjects suffering from major depressive …

Converging lines of research suggest that the hippocampal complex (HC) may have a role
in the pathophysiology of major depressive disorder (MDD). Although postmortem studies …