The epidemiology of esophageal adenocarcinoma
HG Coleman, SH Xie, J Lagergren - Gastroenterology, 2018 - Elsevier
The incidence of esophageal adenocarcinoma (EAC) has increased in many Western
countries and is higher in men than women. Some risk factors for EAC have been identified …
countries and is higher in men than women. Some risk factors for EAC have been identified …
Insights into pathogenic interactions among environment, host, and tumor at the crossroads of molecular pathology and epidemiology
S Ogino, JA Nowak, T Hamada… - Annual Review of …, 2019 - annualreviews.org
Evidence indicates that diet, nutrition, lifestyle, the environment, the microbiome, and other
exogenous factors have pathogenic roles and also influence the genome, epigenome …
exogenous factors have pathogenic roles and also influence the genome, epigenome …
Integrative analysis of exogenous, endogenous, tumour and immune factors for precision medicine
Immunotherapy strategies targeting immune checkpoints such as the CTLA4 and CD274
(programmed cell death 1 ligand 1, PD-L1)/PDCD1 (programmed cell death 1, PD-1) T-cell …
(programmed cell death 1 ligand 1, PD-L1)/PDCD1 (programmed cell death 1, PD-1) T-cell …
[HTML][HTML] Lifestyle, diet, and colorectal cancer risk according to (epi) genetic instability: current evidence and future directions of molecular pathological epidemiology
LAE Hughes, CCJM Simons, PA van den Brandt… - … colorectal cancer reports, 2017 - Springer
Abstract Purpose of Review In this review, we describe molecular pathological epidemiology
(MPE) studies from around the world that have studied diet and/or lifestyle factors in relation …
(MPE) studies from around the world that have studied diet and/or lifestyle factors in relation …
Integration of microbiology, molecular pathology, and epidemiology: a new paradigm to explore the pathogenesis of microbiome‐driven neoplasms
T Hamada, JA Nowak, DA Milner Jr… - The Journal of …, 2019 - Wiley Online Library
Molecular pathological epidemiology (MPE) is an integrative transdisciplinary field that
addresses heterogeneous effects of exogenous and endogenous factors (collectively …
addresses heterogeneous effects of exogenous and endogenous factors (collectively …
Utility of inverse probability weighting in molecular pathological epidemiology
As one of causal inference methodologies, the inverse probability weighting (IPW) method
has been utilized to address confounding and account for missing data when subjects with …
has been utilized to address confounding and account for missing data when subjects with …
Energy sensing pathways: Bridging type 2 diabetes and colorectal cancer?
The recently rapid increase of obesity and type 2 diabetes mellitus has caused great burden
to our society. A positive association between type 2 diabetes and risk of colorectal cancer …
to our society. A positive association between type 2 diabetes and risk of colorectal cancer …
[HTML][HTML] NSAID use and somatic exomic mutations in Barrett's esophagus
PC Galipeau, KM Oman, TG Paulson, CA Sanchez… - Genome Medicine, 2018 - Springer
Background Use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) has
been shown to protect against tetraploidy, aneuploidy, and chromosomal alterations in the …
been shown to protect against tetraploidy, aneuploidy, and chromosomal alterations in the …
[HTML][HTML] Integration of pharmacology, molecular pathology, and population data science to support precision gastrointestinal oncology
Precision medicine has a goal of customizing disease prevention and treatment strategies.
Under the precision medicine paradigm, each patient has unique pathologic processes …
Under the precision medicine paradigm, each patient has unique pathologic processes …
MABp1 for the treatment of colorectal cancer
G O'Sullivan Coyne, M Burotto - Expert Opinion on Biological …, 2017 - Taylor & Francis
Introduction: Inflammation is an established process in colorectal cancer development and a
hallmark of progression, and pro-inflammatory cytokines have been implicated in the …
hallmark of progression, and pro-inflammatory cytokines have been implicated in the …