Polysaccharides, proteins, and synthetic polymers based multimodal hydrogels for various biomedical applications: A review

A Kumar, A Sood, G Agrawal, S Thakur… - International Journal of …, 2023 - Elsevier
Nature-derived or biologically encouraged hydrogels have attracted considerable interest in
numerous biomedical applications owing to their multidimensional utility and effectiveness …

[HTML][HTML] Injectable hydrogels in central nervous system: Unique and novel platforms for promoting extracellular matrix remodeling and tissue engineering

E Hasanzadeh, A Seifalian, A Mellati, J Saremi… - Materials Today Bio, 2023 - Elsevier
Repairing central nervous system (CNS) is difficult due to the inability of neurons to recover
after damage. A clinically acceptable treatment to promote CNS functional recovery and …

Hydrogel oxygen reservoirs increase functional integration of neural stem cell grafts by meeting metabolic demands

Y Wang, ER Zoneff, JW Thomas, N Hong… - Nature …, 2023 - nature.com
Injectable biomimetic hydrogels have great potential for use in regenerative medicine as
cellular delivery vectors. However, they can suffer from issues relating to hypoxia, including …

[HTML][HTML] Biomaterials to enhance stem cell transplantation

BN Kharbikar, P Mohindra, TA Desai - Cell Stem Cell, 2022 - cell.com
The successful transplantation of stem cells has the potential to transform regenerative
medicine approaches and open promising avenues to repair, replace, and regenerate …

Biomaterials for cell transplantation

N Mitrousis, A Fokina, MS Shoichet - Nature Reviews Materials, 2018 - nature.com
Cell transplantation holds immense potential for reversing diseases that are currently
incurable and for regenerating tissues. However, poor cell survival, cell aggregation and …

Applications of human brain organoids to clinical problems

HI Chen, H Song, G Ming - Developmental Dynamics, 2019 - Wiley Online Library
Brain organoids are an exciting new technology with the potential to significantly change
how diseases of the brain are understood and treated. These three‐dimensional neural …

A selective, hydrogel‐based prodrug delivery system efficiently activates a suicide gene to remove undifferentiated human stem cells within neural grafts

KCL Law, N Mahmoudi, ZE Zadeh… - Advanced Functional …, 2023 - Wiley Online Library
The directed differentiation of human pluripotent stem cells (hPSCs) into defined populations
has advanced regenerative medicine, especially for Parkinson's disease where clinical trials …

Activity in grafted human iPS cell–derived cortical neurons integrated in stroke-injured rat brain regulates motor behavior

S Palma-Tortosa, D Tornero… - Proceedings of the …, 2020 - National Acad Sciences
Stem cell transplantation can improve behavioral recovery after stroke in animal models but
whether stem cell–derived neurons become functionally integrated into stroke-injured brain …

3D printed hydrogels with aligned microchannels to guide neural stem cell migration

C Li, M Kuss, Y Kong, F Nie, X Liu, B Liu… - ACS Biomaterials …, 2021 - ACS Publications
Following traumatic or ischemic brain injury, rapid cell death and extracellular matrix
degradation lead to the formation of a cavity at the brain lesion site, which is responsible for …

Mechanobiological strategies to enhance stem cell functionality for regenerative medicine and tissue engineering

M Shafiq, O Ali, SB Han, DH Kim - Frontiers in Cell and …, 2021 - frontiersin.org
Stem cells have been extensively used in regenerative medicine and tissue engineering;
however, they often lose their functionality because of the inflammatory microenvironment …