Polysaccharides, proteins, and synthetic polymers based multimodal hydrogels for various biomedical applications: A review
Nature-derived or biologically encouraged hydrogels have attracted considerable interest in
numerous biomedical applications owing to their multidimensional utility and effectiveness …
numerous biomedical applications owing to their multidimensional utility and effectiveness …
[HTML][HTML] Injectable hydrogels in central nervous system: Unique and novel platforms for promoting extracellular matrix remodeling and tissue engineering
Repairing central nervous system (CNS) is difficult due to the inability of neurons to recover
after damage. A clinically acceptable treatment to promote CNS functional recovery and …
after damage. A clinically acceptable treatment to promote CNS functional recovery and …
Hydrogel oxygen reservoirs increase functional integration of neural stem cell grafts by meeting metabolic demands
Injectable biomimetic hydrogels have great potential for use in regenerative medicine as
cellular delivery vectors. However, they can suffer from issues relating to hypoxia, including …
cellular delivery vectors. However, they can suffer from issues relating to hypoxia, including …
[HTML][HTML] Biomaterials to enhance stem cell transplantation
The successful transplantation of stem cells has the potential to transform regenerative
medicine approaches and open promising avenues to repair, replace, and regenerate …
medicine approaches and open promising avenues to repair, replace, and regenerate …
Biomaterials for cell transplantation
N Mitrousis, A Fokina, MS Shoichet - Nature Reviews Materials, 2018 - nature.com
Cell transplantation holds immense potential for reversing diseases that are currently
incurable and for regenerating tissues. However, poor cell survival, cell aggregation and …
incurable and for regenerating tissues. However, poor cell survival, cell aggregation and …
Applications of human brain organoids to clinical problems
Brain organoids are an exciting new technology with the potential to significantly change
how diseases of the brain are understood and treated. These three‐dimensional neural …
how diseases of the brain are understood and treated. These three‐dimensional neural …
A selective, hydrogel‐based prodrug delivery system efficiently activates a suicide gene to remove undifferentiated human stem cells within neural grafts
The directed differentiation of human pluripotent stem cells (hPSCs) into defined populations
has advanced regenerative medicine, especially for Parkinson's disease where clinical trials …
has advanced regenerative medicine, especially for Parkinson's disease where clinical trials …
Activity in grafted human iPS cell–derived cortical neurons integrated in stroke-injured rat brain regulates motor behavior
S Palma-Tortosa, D Tornero… - Proceedings of the …, 2020 - National Acad Sciences
Stem cell transplantation can improve behavioral recovery after stroke in animal models but
whether stem cell–derived neurons become functionally integrated into stroke-injured brain …
whether stem cell–derived neurons become functionally integrated into stroke-injured brain …
3D printed hydrogels with aligned microchannels to guide neural stem cell migration
Following traumatic or ischemic brain injury, rapid cell death and extracellular matrix
degradation lead to the formation of a cavity at the brain lesion site, which is responsible for …
degradation lead to the formation of a cavity at the brain lesion site, which is responsible for …
Mechanobiological strategies to enhance stem cell functionality for regenerative medicine and tissue engineering
Stem cells have been extensively used in regenerative medicine and tissue engineering;
however, they often lose their functionality because of the inflammatory microenvironment …
however, they often lose their functionality because of the inflammatory microenvironment …