Computational methods for the segmentation of images of objects from background in a flow imaging instrument

KL Frost, JK Riley - US Patent 7,190,832, 2007 - Google Patents
In automated computation-based interpretation of images, the accuracy and reliability of the
detection and delineation of objects, known as “object segmentation,” is implemented So as …

Microholographic multilayer optical disk data storage

RR McLeod, AJ Daiber, ME McDonald, TL Robertson… - Applied …, 2005 - opg.optica.org
Micrometer-sized reflection holograms can be written into a rapidly rotating homogeneous
photopolymer disk at the focus of a high-numerical-aperture beam and its retroreflection to …

Blood and cell analysis using an imaging flow cytometer

W Ortyn, D Basiji, P Morrissey, T George, B Hall… - US Patent …, 2013 - Google Patents
Multimodal or multispectral images of cells comprising a population of cells are
simultaneously collected. Photometric and/or morphometric image features identifiable in …

Detection of circulating tumor cells using imaging flow cytometry

W Ortyn, D Basiji, L Liang, V Venkatachalam… - US Patent …, 2012 - Google Patents
Continuation-in-part of application No. 1 1/344.941, filed on Feb. 1, 2006, now Pat. No.
7,522,758, and a continuation of application No. 1 1/123,610, filed on May 4, 2005, now Pat …

Extended depth of field imaging for high speed object analysis

W Ortyn, D Basiji, K Frost, L Liang, R Bauer… - US Patent …, 2011 - Google Patents
(57) ABSTRACT A high speed, high-resolution flow imaging system is modi fied to achieve
extended depth of field imaging. An optical distortion element is introduced into the flow …

Method for imaging and differential analysis of cells

TC George, DA Basiji, BE Hall, WE Ortyn… - US Patent …, 2012 - Google Patents
Provided are methods for determining and analyzing photo metric and morphogenic
features of Small objects, such as cells to, for example, identify different cell states. In particu …

Blood and cell analysis using an imaging flow cytometer

WE Ortyn, DA Basiji, P Morrissey, T George… - US Patent …, 2011 - Google Patents
Related US Application Data (60) division of application No. 1 1/344.941, filed on Feb. 1,
2006, now Pat. No. 7,522,758, which is a continuation-in-part of application No. 1 1/123,610 …

Imaging and analyzing parameters of small moving objects such as cells

WE Ortyn, DA Basiji - US Patent 7,315,357, 2008 - Google Patents
Light from an object such as a cell moving through an imaging system is collected and
dispersed so that it is imaged onto a plurality of separate detectors. The light is spectrally …

Blood and cell analysis using an imaging flow cytometer

WE Ortyn, DA Basiji, P Morrissey, T George… - US Patent …, 2009 - Google Patents
Related US Application Data(74) Attorney, Agent, or Firm—Rona CSO (63) Continuation-in-
part of application No. 1 1/123,610,(57) ABSTRACT filed on May 4, 2005, now Pat. No …

Methods for analyzing inter-cellular phenomena

WE Ortyn, DA Basiji, DH Lynch - US Patent 7,450,229, 2008 - Google Patents
Aspects of the present invention encompass the collection of multispectral images from a
population of objects, and the analysis of the collected images to measure at least one …