Vaccine-Induced Cellular Immunity against Bordetella pertussis: Harnessing Lessons from Animal and Human Studies to Improve Design and Testing of Novel …
A Saso, B Kampmann, S Roetynck - Vaccines, 2021 - mdpi.com
Pertussis ('whooping cough') is a severe respiratory tract infection that primarily affects
young children and unimmunised infants. Despite widespread vaccine coverage, it remains …
young children and unimmunised infants. Despite widespread vaccine coverage, it remains …
Antibody persistence 2 and 3 years after booster vaccination of adolescents with recombinant acellular pertussis monovalent aPgen or combined TdaPgen vaccines
P Pitisuttithum, J Dhitavat, C Sirivichayakul… - …, 2021 - thelancet.com
Background Recombinant pertussis vaccines inducing long-lasting immune responses
could help to control the rise in pertussis. We here report on persisting antibody responses 2 …
could help to control the rise in pertussis. We here report on persisting antibody responses 2 …
Antibody persistence after vaccination of adolescents with monovalent and combined acellular pertussis vaccines containing genetically inactivated pertussis toxin: a …
P Pitisuttithum, K Chokephaibulkit… - The Lancet Infectious …, 2018 - thelancet.com
Background The immunogenicity of acellular pertussis vaccines and persistence of immunity
after vaccination might be improved by using genetically inactivated pertussis toxin (PTgen) …
after vaccination might be improved by using genetically inactivated pertussis toxin (PTgen) …
Genetically detoxified pertussis toxin displays near identical structure to its wild-type and exhibits robust immunogenicity
SF Ausar, S Zhu, J Duprez, M Cohen… - Communications …, 2020 - nature.com
Abstract The mutant gdPT R9K/E129G is a genetically detoxified variant of the pertussis
toxin (PTx) and represents an attractive candidate for the development of improved pertussis …
toxin (PTx) and represents an attractive candidate for the development of improved pertussis …
Immunological distinctions between acellular and whole-cell pertussis immunizations of baboons persist for at least one year after acellular vaccine boosting
LE Cole, J Zhang, KM Pacheco, P Lhéritier… - Vaccines, 2020 - mdpi.com
While both whole-cell (wP) and acellular pertussis (aP) vaccines have been highly effective
at reducing the global pertussis disease burden, there are concerns that compared to wP …
at reducing the global pertussis disease burden, there are concerns that compared to wP …
Pediatric vaccine hesitancy and the utilization of antibody measurements: a novel strategy with implications for COVID 19
A Dosanjh - Journal of Asthma and Allergy, 2021 - Taylor & Francis
Vaccine hesitancy is a well researched area with implications for both public health and the
health of children and their families The factors leading to vaccine hesitancy are often …
health of children and their families The factors leading to vaccine hesitancy are often …
A phase-I, open label clinical trial to assess the safety of Tdap vaccine manufactured by Serum Institute of India Pvt. Ltd. in adults
H Sharma, K Anil, S Parekh, P Pujari, S Shewale… - Vaccine, 2021 - Elsevier
Background This first in human study was designed as an open label clinical trial to assess
the safety and tolerability of Serum Institute of India Pvt. Ltd.(SIIPL) Tdap vaccine in healthy …
the safety and tolerability of Serum Institute of India Pvt. Ltd.(SIIPL) Tdap vaccine in healthy …