The psychosis high-risk state: a comprehensive state-of-the-art review
Context During the past 2 decades, a major transition in the clinical characterization of
psychotic disorders has occurred. The construct of a clinical high-risk (HR) state for …
psychotic disorders has occurred. The construct of a clinical high-risk (HR) state for …
Disorder, not just state of risk: meta-analysis of functioning and quality of life in people at high risk of psychosis
BackgroundThe nosology of the psychosis high-risk state is controversial. Traditionally
conceived as an 'at risk'state for the development of psychotic disorders, it is also …
conceived as an 'at risk'state for the development of psychotic disorders, it is also …
Predicting psychosis: meta-analysis of transition outcomes in individuals at high clinical risk
Context A substantial proportion of people at clinical high risk of psychosis will develop a
psychotic disorder over time. However, the risk of transition to psychosis varies between …
psychotic disorder over time. However, the risk of transition to psychosis varies between …
Long-term follow-up of a group at ultra high risk (“prodromal”) for psychosis: the PACE 400 study
Importance The ultra high-risk (UHR) criteria were introduced to prospectively identify
patients at high risk of psychotic disorder. Although the short-term outcome of UHR patients …
patients at high risk of psychotic disorder. Although the short-term outcome of UHR patients …
Dysfunction of ventral striatal reward prediction in schizophrenia
Background: Negative symptoms may be associated with dysfunction of the brain reward
system in schizophrenia. We used functional magnetic resonance imaging (fMRI) to assess …
system in schizophrenia. We used functional magnetic resonance imaging (fMRI) to assess …
Use of neuroanatomical pattern classification to identify subjects in at-risk mental states of psychosis and predict disease transition
N Koutsouleris, EM Meisenzahl… - Archives of general …, 2009 - jamanetwork.com
Context Identification of individuals at high risk of developing psychosis has relied on
prodromal symptomatology. Recently, machine learning algorithms have been successfully …
prodromal symptomatology. Recently, machine learning algorithms have been successfully …
Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the treatment of schizophrenia and related disorders.
R Australian - Australian & New Zealand Journal of …, 2005 - search.ebscohost.com
Abstract BACKGROUND: The Royal Australian and New Zealand College of Psychiatrists is
co-ordinating the development of clinical practice guidelines (CPGs) in psychiatry, funded …
co-ordinating the development of clinical practice guidelines (CPGs) in psychiatry, funded …
Prediction of psychosis by mismatch negativity
M Bodatsch, S Ruhrmann, M Wagner, R Müller… - Biological …, 2011 - Elsevier
BACKGROUND:: To develop risk-adapted prevention of psychosis, an accurate estimation
of the individual risk of psychosis at a given time is needed. Inclusion of biological …
of the individual risk of psychosis at a given time is needed. Inclusion of biological …
Clinical staging: a heuristic and practical strategy for new research and better health and social outcomes for psychotic and related mood disorders
PD McGorry, B Nelson, S Goldstone… - … Canadian Journal of …, 2010 - journals.sagepub.com
Most mental illnesses emerge during adolescence and early adulthood, with considerable
associated distress and functional decline appearing during this critical developmental …
associated distress and functional decline appearing during this critical developmental …
Intervention in individuals at ultra high risk for psychosis: a review and future directions
Objective: Over the last 15 years, a focus on early intervention in psychotic disorders has
emerged. Initially, the early psychosis movement focused on timely recognition and phase …
emerged. Initially, the early psychosis movement focused on timely recognition and phase …