Over-distension prediction via hysteresis loop analysis and patient-specific basis functions in a virtual patient model

Q Sun, JG Chase, C Zhou, MH Tawhai… - Computers in Biology …, 2022 - Elsevier
Background and objective Recruitment maneuvers (RMs) with subsequent positive-end-
expiratory-pressure (PEEP) have proven effective in recruiting lung volume and preventing …

Model-based glycemic control in a Malaysian intensive care unit: performance and safety study

A Abu-Samah, JL Knopp, NN Abdul Razak… - Medical Devices …, 2019 - Taylor & Francis
Background: Stress-induced hyperglycemia is common in critically ill patients. A few forms of
model-based glycemic control have been introduced to reduce this phenomena and among …

Electroencephalogram spectral moments for the detection of nocturnal hypoglycemia

CQ Ngo, R Chai, TV Nguyen, TW Jones… - IEEE journal of …, 2019 - ieeexplore.ieee.org
Hypoglycemia or low blood glucose is the most feared complication of insulin treatment of
diabetes. For people with diabetes, the mismatch between the insulin therapy and the body's …

Pulmonary response prediction through personalized basis functions in a virtual patient model

T Caljé-van der Klei, Q Sun, JG Chase, C Zhou… - Computer Methods and …, 2024 - Elsevier
Abstract Background and Objective Recruitment maneuvers with subsequent positive-end-
expiratory-pressure (PEEP) have proven effective in recruiting lung volume and preventing …

The effect of hypoglycemia on spectral moments in EEG epochs of different durations in type 1 diabetes patients

CQ Ngo, R Chai, TW Jones… - IEEE Journal of …, 2021 - ieeexplore.ieee.org
The potential of using an electroencephalogram (EEG) to detect hypoglycemia in patients
with type 1 diabetes (T1D) has been investigated in both time and frequency domains …

Nocturnal hypoglycemia detection using EEG spectral moments under natural occurrence conditions

CQ Ngo, R Chai, TV Nguyen, TW Jones… - 2019 41st Annual …, 2019 - ieeexplore.ieee.org
This paper is concerned with a study of hypoglycemia under natural occurrence conditions
at night time. Five adolescents with type 1 diabetes (T1D) participated in the experiments …

[HTML][HTML] Comparison of three artificial intelligence methods for predicting 90% quantile interval of future insulin sensitivity of intensive care patients

B Szabó, Á Szlávecz, B Paláncz, OS Alkhafaf… - IFAC Journal of Systems …, 2024 - Elsevier
Insulin dosing of hyperglycemic patients in the intensive care unit (ICU) is a complex and
nonlinear clinical control problem. Recent model-based glycemic control protocols predict a …

Clinical trial validation of the STAR-3D glycemic control framework

V Uyttendaele, JL Knopp, T Desaive, JG Chase - IFAC-PapersOnLine, 2023 - Elsevier
Glycemic control (GC) to regulate dysglycemia in critically ill patients is associated with
improved outcomes. However, it has been hard to achieve safely due to metabolic …

Translating A Risk-Based Glycaemic Control Framework for Critically Ill Patients: STAR-Liège

V Uyttendaele, JL Knopp, M Pirotte, P Morimont… - IFAC …, 2020 - orbi.uliege.be
Glycaemic control (GC) in the intensive care unit (ICU) has been widely debated over the
last 20 years. While many studies showed benefits, many others failed to replicate the …

The goldilocks problem: Nutrition and its impact on glycaemic control

JL Knopp, JG Chase, GM Shaw - Clinical Nutrition, 2021 - Elsevier
Background Glucose intolerance and insulin resistance manifest as hyperglycaemia in
intensive care, which is associated with mortality and morbidities. Glycaemic control (GC) …