Progress of genome wide association study in domestic animals

H Zhang, Z Wang, S Wang, H Li - Journal of animal science and …, 2012 - Springer
Domestic animals are invaluable resources for study of the molecular architecture of
complex traits. Although the mapping of quantitative trait loci (QTL) responsible for …

PLAG1 and NCAPG‐LCORL in livestock

A Takasuga - Animal Science Journal, 2016 - Wiley Online Library
A recent progress on stature genetics has revealed simple genetic architecture in livestock
animals in contrast to that in humans. PLAG1 and/or NCAPG‐LCORL, both of which are …

Genome-wide association study for feed efficiency and growth traits in US beef cattle

CM Seabury, DL Oldeschulte, M Saatchi, JE Beever… - BMC genomics, 2017 - Springer
Background Single nucleotide polymorphism (SNP) arrays for domestic cattle have
catalyzed the identification of genetic markers associated with complex traits for inclusion in …

Large-effect pleiotropic or closely linked QTL segregate within and across ten US cattle breeds

M Saatchi, RD Schnabel, JF Taylor, DJ Garrick - BMC genomics, 2014 - Springer
Background The availability of high-density SNP assays including the BovineSNP50 (50 K)
enables the identification of novel quantitative trait loci (QTL) and improvement of the …

Genotyping-by-sequencing (GBS): a novel, efficient and cost-effective genotyping method for cattle using next-generation sequencing

M De Donato, SO Peters, SE Mitchell, T Hussain… - PloS one, 2013 - journals.plos.org
High-throughput genotyping methods have increased the analytical power to study complex
traits but high cost has remained a barrier for large scale use in animal improvement. We …

GWAS and fine-mapping of livability and six disease traits in Holstein cattle

E Freebern, DJA Santos, L Fang, J Jiang… - BMC genomics, 2020 - Springer
Background Health traits are of significant economic importance to the dairy industry due to
their effects on milk production and associated treatment costs. Genome-wide association …

Genome-wide association study identifies loci for body composition and structural soundness traits in pigs

B Fan, SK Onteru, ZQ Du, DJ Garrick, KJ Stalder… - PloS one, 2011 - journals.plos.org
Background The recent completion of the swine genome sequencing project and
development of a high density porcine SNP array has made genome-wide association …

Genome-wide association study identified three major QTL for carcass weight including the PLAG1-CHCHD7 QTN for stature in Japanese Black cattle

S Nishimura, T Watanabe, K Mizoshita, K Tatsuda… - BMC genetics, 2012 - Springer
Background Significant quantitative trait loci (QTL) for carcass weight were previously
mapped on several chromosomes in Japanese Black half-sib families. Two QTL, CW-1 and …

Genome-wide association studies of female reproduction in tropically adapted beef cattle

RJ Hawken, YD Zhang, MRS Fortes… - Journal of animal …, 2012 - academic.oup.com
The genetics of reproduction is poorly understood because the heritabilities of traits currently
recorded are low. To elucidate the genetics underlying reproduction in beef cattle, we …

Evidence for pleiotropism and recent selection in the PLAG1 region in Australian Beef cattle

MRS Fortes, K Kemper, S Sasazaki, A Reverter… - Animal …, 2013 - Wiley Online Library
A putative functional mutation (rs109231213) near PLAG 1 (BTA 14) associated with stature
was studied in beef cattle. Data from 8199 B os taurus, B os indicus and T ropical C …