Abstract The Hedgehog (Hh) signaling pathway was first identified in the common fruit fly. It
is a highly conserved evolutionary pathway of signal transmission from the cell membrane to …

Simple Summary The Hedgehog/GLI (Hh/GLI) pathway plays a major role during
development and it is commonly dysregulated in many diseases, including cancer. This …

Circular RNAs (circRNAs) are identified as vital regulators in a variety of cancers. However,
the role of circRNA in lung squamous cell carcinoma (LUSC) remains largely unknown …

FOXM1 (forkhead box protein M1) is a critical proliferation-associated transcription factor
that is widely spatiotemporally expressed during the cell cycle. It is closely involved with the …

The hedgehog (HH) signaling pathway regulates normal cell growth and differentiation. As a
consequence of improper control, aberrant HH signaling results in tumorigenesis and …

Forkhead box transcription factor, FOXM1 is implicated in several cellular processes such as
proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue …

FOXM1 is frequently overexpressed in cancer, but this has not been studied in a
comprehensive manner. We utilized genotype-tissue expression (GTEx) normal and The …

Pancreatic ductal adenocarcinoma (PDAC) is characterized by near-universal mutations in
KRAS and frequent deregulation of crucial embryonic signalling pathways, including the …

Forkhead box (Fox) proteins are a superfamily of evolutionarily conserved transcriptional
regulators, which control a wide spectrum of biological processes. As a consequence, a loss …

Forkhead-box (FOX) family proteins, involved in cell growth and differentiation as well as
embryogenesis and longevity, are DNA-binding proteins regulating transcription and DNA …