Anhedonia is associated with suicidal ideation independently of depression: A meta‐analysis

D Ducasse, G Loas, D Dassa… - Depression and …, 2018 - Wiley Online Library
Background Anhedonia is considered a suicide risk factor in patients with major affective
disorders. Here, we wanted to quantify the association between anhedonia and current …

An excitatory synapse hypothesis of depression

SM Thompson, AJ Kallarackal, MD Kvarta… - Trends in …, 2015 - cell.com
Depression is a common cause of mortality and morbidity, but the biological bases of the
deficits in emotional and cognitive processing remain incompletely understood. Current …

Positive affect treatment for depression and anxiety: A randomized clinical trial for a core feature of anhedonia.

MG Craske, AE Meuret, T Ritz, M Treanor… - Journal of consulting …, 2019 - psycnet.apa.org
Objective: Loss of pleasure or interest in activities (ie, anhedonia) is a risk factor for
suicidality, treatment nonresponse, and relapse. Extant treatments that focus on reducing …

Positive affect treatment targets reward sensitivity: A randomized controlled trial.

MG Craske, AE Meuret, A Echiverri-Cohen… - Journal of consulting …, 2023 - psycnet.apa.org
Objective: Determine whether a novel psychosocial treatment for positive affect improves
clinical status and reward sensitivity more than a form of cognitive behavioral therapy that …

Treatment for anhedonia: A neuroscience driven approach

MG Craske, AE Meuret, T Ritz, M Treanor… - Depression and …, 2016 - Wiley Online Library
Anhedonia, or loss of interest or pleasure in usual activities, is characteristic of depression,
some types of anxiety, as well as substance abuse and schizophrenia. Anhedonia is a …

Stress to inflammation and anhedonia: Mechanistic insights from preclinical and clinical models

CC Boyle, JE Bower, NI Eisenberger… - … & Biobehavioral Reviews, 2023 - Elsevier
Anhedonia, as evidenced by impaired pleasurable response to reward, reduced reward
motivation, and/or deficits in reward-related learning, is a common feature of depression …

Suicide Crisis Syndrome: A review of supporting evidence for a new suicide‐specific diagnosis

A Schuck, R Calati, S Barzilay… - … sciences & the law, 2019 - Wiley Online Library
Suicide is a major public health problem, and suicide rates are still on the rise. Current
strategies for identifying individuals at risk for suicide, such as the use of a patient's self …

The role of cytokines in the pathophysiology of suicidal behavior

L Ganança, MA Oquendo, AR Tyrka… - …, 2016 - Elsevier
Objective Immune dysregulation has been implicated in depression and other psychiatric
disorders. What is less clear is how immune dysregulation can affect risk of suicidal …

Effects of physical exercise on depressive symptoms and biomarkers in depression

T Archer, T Josefsson, M Lindwall - CNS & Neurological …, 2014 - ingentaconnect.com
Regular physical exercise/activity has been shown repeatedly to promote positive benefits in
cognitive, emotional and motor domains concomitant with reductions in distress and …

Anhedonia as a clinical correlate of suicidal thoughts in clinical ketamine trials

ED Ballard, K Wills, N Lally, EM Richards… - Journal of affective …, 2017 - Elsevier
Background Identifying clinical correlates associated with reduced suicidal ideation may
highlight new avenues for the treatment of suicidal thoughts. Anhedonia occurs across …