Comorbidities, multimorbidity and COVID-19

CD Russell, NI Lone, JK Baillie - Nature medicine, 2023 - nature.com
The influence of comorbidities on COVID-19 outcomes has been recognized since the
earliest days of the pandemic. But establishing causality and determining underlying …

Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?

SJ Kent, DS Khoury, A Reynaldi, JA Juno… - Nature Reviews …, 2022 - nature.com
The rapid development of multiple vaccines providing strong protection from severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been a major achievement …

Epidemiology and outcomes of COVID-19 in HIV-infected individuals: a systematic review and meta-analysis

P Ssentongo, ES Heilbrunn, AE Ssentongo, S Advani… - Scientific reports, 2021 - nature.com
Susceptibility to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
and the risk of mortality among people living with human immunodeficiency virus …

Associations between HIV infection and clinical spectrum of COVID-19: a population level analysis based on US National COVID Cohort Collaborative (N3C) data

X Yang, J Sun, RC Patel, J Zhang, S Guo, Q Zheng… - The Lancet …, 2021 - thelancet.com
Background Evidence of whether people living with HIV are at elevated risk of adverse
COVID-19 outcomes is inconclusive. We aimed to investigate this association using the …

Overview of SARS-CoV-2 infection in adults living with HIV

J Ambrosioni, JL Blanco, JM Reyes-Urueña… - The lancet HIV, 2021 - thelancet.com
Around 2· 5 million deaths and more than 110 million COVID-19 cases have been reported
globally. Although it initially appeared that HIV infection was not a risk factor for COVID-19 or …

Prognostic factors for mortality, intensive care unit and hospital admission due to SARS-CoV-2: a systematic review and meta-analysis of cohort studies in Europe

CI Vardavas, AG Mathioudakis… - European …, 2022 - Eur Respiratory Soc
Background As mortality from coronavirus disease 2019 (COVID-19) is strongly age-
dependent, we aimed to identify population subgroups at an elevated risk for adverse …

The burden of COVID-19 in the immunocompromised patient: implications for vaccination and needs for the future

A Antinori, M Bausch-Jurken - The Journal of Infectious …, 2023 - academic.oup.com
Approximately 3% of US adults are immunocompromised and less capable of fighting
infections such as SARS-CoV-2 (the causative agent of COVID-19). Individuals may be …

Humoral immune responses to COVID-19 vaccination in people living with HIV receiving suppressive antiretroviral therapy

ZL Brumme, F Mwimanzi, HR Lapointe, PK Cheung… - npj Vaccines, 2022 - nature.com
Humoral responses to COVID-19 vaccines in people living with HIV (PLWH) remain
incompletely characterized. We measured circulating antibodies against the SARS-CoV-2 …

Characterization of humoral and SARS-CoV-2 specific T cell responses in people living with HIV

A Alrubayyi, E Gea-Mallorquí, E Touizer… - Nature …, 2021 - nature.com
There is an urgent need to understand the nature of immune responses against SARS-CoV-
2, to inform risk-mitigation strategies for people living with HIV (PLWH). Here we show that …

Risk of adverse coronavirus disease 2019 outcomes for people living with HIV

MM Mellor, AC Bast, NR Jones, NW Roberts… - Aids, 2021 - journals.lww.com
Objective: To assess whether people living with HIV (PLWH) are at increased risk of
coronavirus disease 2019 (COVID-19) mortality or adverse outcomes, and whether …