[HTML][HTML] Epstein–Barr virus: more than 50 years old and still providing surprises

LS Young, LF Yap, PG Murray - Nature reviews cancer, 2016 - nature.com
It is more than 50 years since the Epstein–Barr virus (EBV), the first human tumour virus, was
discovered. EBV has subsequently been found to be associated with a diverse range of …

The role of Epstein–Barr virus in nasopharyngeal carcinoma

ZY Su, PY Siak, CO Leong, SC Cheah - Frontiers in Microbiology, 2023 - frontiersin.org
Nasopharyngeal carcinoma (NPC) is a metastasis-prone malignancy closely associated
with the Epstein–Barr virus (EBV). Despite ubiquitous infection of EBV worldwide, NPC …

The role of Epstein–Barr virus in epithelial malignancies

SW Tsao, CM Tsang, KF To, KW Lo - The Journal of pathology, 2015 - Wiley Online Library
The close association of Epstein–Barr virus (EBV) infection with non‐keratinizing
nasopharyngeal carcinomas and a subset of gastric carcinomas suggests that EBV infection …

Genome diversity of Epstein-Barr virus from multiple tumor types and normal infection

AL Palser, NE Grayson, RE White, C Corton… - Journal of …, 2015 - Am Soc Microbiol
Epstein-Barr virus (EBV) infects most of the world's population and is causally associated
with several human cancers, but little is known about how EBV genetic variation might …

Epstein‐Barr virus strain variation and cancer

T Kanda, M Yajima, K Ikuta - Cancer science, 2019 - Wiley Online Library
Epstein‐Barr virus (EBV) is a human tumor virus and is etiologically linked to various
malignancies. Certain EBV‐associated diseases, such as Burkitt lymphomas and …

Nasopharyngeal carcinoma: a review

F Petersson - Seminars in diagnostic pathology, 2015 - Elsevier
Nasopharyngeal carcinoma is an umbrella term for a group of malignant epithelial tumors
with different etiopathogenesis and a broad range of histopathological appearances. Some …

[HTML][HTML] Spontaneous lytic replication and epitheliotropism define an Epstein-Barr virus strain found in carcinomas

MH Tsai, A Raykova, O Klinke, K Bernhardt, K Gärtner… - Cell reports, 2013 - cell.com
Summary The Epstein-Barr virus (EBV) is found in a variety of tumors whose incidence
greatly varies around the world. A poorly explored hypothesis is that particular EBV strains …

Challenges and opportunities in estimating viral genetic diversity from next-generation sequencing data

N Beerenwinkel, HF Günthard, V Roth… - Frontiers in …, 2012 - frontiersin.org
Many viruses, including the clinically relevant RNA viruses HIV (human immunodeficiency
virus) and HCV (hepatitis C virus), exist in large populations and display high genetic …

Epstein-Barr virus sequence variation—biology and disease

S Tzellos, PJ Farrell - Pathogens, 2012 - mdpi.com
Some key questions in Epstein-Barr virus (EBV) biology center on whether naturally
occurring sequence differences in the virus affect infection or EBV associated diseases …

[HTML][HTML] Next-generation sequencing technology in clinical virology

MR Capobianchi, E Giombini, G Rozera - Clinical Microbiology and …, 2013 - Elsevier
Recent advances in nucleic acid sequencing technologies, referred to as 'next-generation'
sequencing (NGS), have produced a true revolution and opened new perspectives for …