Understanding the complex and specific roles played by non-coding RNAs (ncRNAs), which
comprise the bulk of the genome, is important for understanding virtually every hallmark of …

Post-transcriptional modifications to coding and non-coding RNAs are unquestionably a
pivotal way in which human mRNA and protein diversity can influence the different phases …

RNA binding proteins (RBPs) contributes to cancer progression, but the underlying
mechanism reminds unclear. Here, we find that DDX21, a representative RBP, is highly …

The utility of circular RNAs (circRNAs) as molecular biomarkers has recently emerged.
However, only a handful of them have already been studied in colorectal cancer (CRC). The …

Cisplatin (CDDP) based chemotherapy is widely used as the first-line strategy in treating
non-small cell lung cancer (NSCLC), especially lung squamous cell carcinoma (LUSC) …

Tumors refractory to conventional therapy belong to specific subpopulations of cancer cells,
which have acquired a higher number of mutations/epigenetic changes than the majority of …

Chemoresistance is closely related to the therapeutic effect and prognosis in breast cancer
patients. Increasing evidences demonstrated that RNA binding proteins (RBPs) have …

Introduction: Ischemic stroke, an abrupt blockage of artery, accounting for the most cases of
stroke, causes high neurological mortality across the world. Recent evidence has uncovered …

Colorectal cancer (CRC) is a malignancy that is both highly lethal and heterogeneous.
Although the correlation between intra-tumoral genetic and functional heterogeneity and …

Early recurrence in patients with colorectal cancer (CRC) is associated with a poor
prognosis. We aimed to identify circulating microRNAs that are biomarkers of early CRC …