Physiology of astroglia

A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

[HTML][HTML] Waste clearance in the brain

J Kaur, LM Fahmy, E Davoodi-Bojd, L Zhang… - Frontiers in …, 2021 - frontiersin.org
Waste clearance (WC) is an essential process for brain homeostasis, which is required for
the proper and healthy functioning of all cerebrovascular and parenchymal brain cells. This …

The glia of the adult Drosophila nervous system

MC Kremer, C Jung, S Batelli, GM Rubin, U Gaul - Glia, 2017 - Wiley Online Library
Glia play crucial roles in the development and homeostasis of the nervous system. While the
GLIA in the Drosophila embryo have been well characterized, their study in the adult …

[HTML][HTML] Histamine, neuroinflammation and neurodevelopment: a review

E Carthy, T Ellender - Frontiers in neuroscience, 2021 - frontiersin.org
The biogenic amine, histamine, has been shown to critically modulate inflammatory
processes as well as the properties of neurons and synapses in the brain, and is also …

[HTML][HTML] More than mortar: glia as architects of nervous system development and disease

I Lago-Baldaia, VM Fernandes… - Frontiers in Cell and …, 2020 - frontiersin.org
Glial cells are an essential component of the nervous system of vertebrates and
invertebrates. In the human brain, glia are as numerous as neurons, yet the importance of …

Cryptochrome 2 mediates directional magnetoreception in cockroaches

O Bazalova, M Kvicalova, T Valkova… - Proceedings of the …, 2016 - National Acad Sciences
The ability to perceive geomagnetic fields (GMFs) represents a fascinating biological
phenomenon. Studies on transgenic flies have provided evidence that photosensitive …

[HTML][HTML] Gap Junctional Blockade Stochastically Induces Different Species-Specific Head Anatomies in Genetically Wild-Type Girardia dorotocephala Flatworms

M Emmons-Bell, F Durant, J Hammelman… - International journal of …, 2015 - mdpi.com
The shape of an animal body plan is constructed from protein components encoded by the
genome. However, bioelectric networks composed of many cell types have their own …

Evolution of neuroglia

A Verkhratsky, MS Ho, V Parpura - Neuroglia in Neurodegenerative …, 2019 - Springer
As the nervous system evolved from the diffused to centralised form, the neurones were
joined by the appearance of the supportive cells, the neuroglia. Arguably, these non …

Gap junctional signaling in pattern regulation: physiological network connectivity instructs growth and form

J Mathews, M Levin - Developmental neurobiology, 2017 - Wiley Online Library
Gap junctions (GJs) are aqueous channels that allow cells to communicate via physiological
signals directly. The role of gap junctional connectivity in determining single‐cell functions …

[HTML][HTML] Implications of glial metabolic dysregulation in the pathophysiology of neurodegenerative diseases

R Afridi, MH Rahman, K Suk - Neurobiology of disease, 2022 - Elsevier
Glial cells are the most abundant cells of the brain, outnumbering neurons. These
multifunctional cells are crucial for maintaining brain homeostasis by providing trophic and …