Nanomedicine revolutionizes epilepsy treatment: overcoming therapeutic hurdles with nanoscale solutions

S Li, W Zhang, Y Zhu, Q Yao, R Chen… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Epilepsy, a prevalent neurodegenerative disorder, profoundly impacts the
physical and mental well-being of millions globally. Historically, antiseizure drugs (ASDs) …

[HTML][HTML] Nanocarriers-based therapeutic strategy for drug-resistant epilepsy: A systematic review

R Diaz-Peregrino, D San-Juan… - International Journal of …, 2024 - Elsevier
Background Nanocarriers have been proposed as a solution for drug-resistant epilepsy.
Methods A systematic review of animal and in vitro studies was conducted to evaluate the …

[HTML][HTML] Development and Evaluation of Docetaxel-Loaded Nanostructured Lipid Carriers for Skin Cancer Therapy

FI Cocoș, V Anuța, L Popa, MV Ghica, MA Nica… - Pharmaceutics, 2024 - mdpi.com
This study focuses on the design, characterization, and optimization of nanostructured lipid
carriers (NLCs) loaded with docetaxel for the treatment of skin cancer. Employing a …

[HTML][HTML] Nanostructured lipid carriers containing benznidazole: physicochemical, biopharmaceutical and cellular in vitro studies

G Muraca, ME Ruiz, RC Gambaro… - Beilstein Journal of …, 2023 - beilstein-journals.org
Chagas disease is a neglected endemic disease prevalent in Latin American countries,
affecting around 8 million people. The first-line treatment, benznidazole (BNZ), is effective in …

Frontiers in therapeutic interventions for epilepsy: nanocarriers as a pivotal catalyst in the synergistic combination of conventional antiepileptics and herbal drugs.

APS Chauhan, D Unnithan, R Alam, H Singh… - Journal of Drug Delivery …, 2024 - Elsevier
Epilepsy, a prevalent and frequently incapacitating neurological disease affecting over 50
million people worldwide, exhibits substantial treatment challenges, particularly in one-third …

Nanocarriers in the Treatment of Epilepsy: Challenges and Opportunities

PB Anjali, N Jawahar, MRP Kumar, S Jubie… - Journal of Drug Delivery …, 2024 - Elsevier
Epilepsy is a disease of the central nervous system that is characterized by recurring
seizures. Because of the complex nature of the brain's protective barriers and the limitations …

On the Development of New Drugs for the Treatment of Drug-Resistant Epilepsy: An Update on Different Approaches to Different Hypotheses

A Talevi - Pharmacoresistance in Epilepsy: From Genes and …, 2023 - Springer
Despite the continuous expansion of the available pharmacological options for the treatment
of epilepsies and remarkable advances in understanding their pathophysiology, the …

Multivariate Optimization of Carbamazepine-Loaded Nanostructured Lipid Carriers for Brain Targeting and Epilepsy Management

P Patel, R Vaidya, Y Kansara, P Shah, DU Kapoor… - BioNanoScience, 2025 - Springer
The growth of nanostructured lipid carriers for brain targeting shows a promising strategy for
escalating the therapeutic efficacy of antiepileptic drugs such as carbamazepine (CBZ). CBZ …

Novel drug delivery systems in treating epilepsy: An update

J Uppal, A Chawla, R Rehman, MS Hussain… - Novel Drug Delivery …, 2025 - Elsevier
Epilepsy is a neurological condition that affects 70 million individuals worldwide. The BBB,
which manages a series of distinctive properties that safely control the transit of chemicals …

[HTML][HTML] Harnessing nanotechnology for enhanced epilepsy management

V Manasa, JJ Ruby, HP Gogoi, S Vignesh… - MGM Journal of …, 2024 - journals.lww.com
Epilepsy, a condition characterized by unprovoked, recurrent seizures, currently has no
cure, with treatments ranging from medications to treatment modalities such as antiepileptic …