Recent advancements of nanomedicine in neurodegenerative disorders theranostics

S Mukherjee, VS Madamsetty… - Advanced Functional …, 2020 - Wiley Online Library
Recent times have witnessed an upsurge in the incidence of neurodegenerative disorders
such as Alzheimer's disease, Parkinson's disease, Huntington's disease, Prion disease, and …

Insights into colloidal nanoparticle-protein corona interactions for nanomedicine applications

M Martínez-Negro, G González-Rubio, E Aicart… - Advances in Colloid and …, 2021 - Elsevier
Colloidal nanoparticles (NPs) have attracted significant attention due to their unique
physicochemical properties suitable for diagnosing and treating different human diseases …

Design of a molecular hybrid of dual peptide inhibitors coupled on AuNPs for enhanced inhibition of amyloid β‐protein aggregation and cytotoxicity

N Xiong, Y Zhao, X Dong, J Zheng, Y Sun - Small, 2017 - Wiley Online Library
Aggregation of amyloid‐β protein (Aβ) is a pathological hallmark of Alzheimer's disease
(AD), so the inhibition of Aβ aggregation is an important strategy for the prevention and …

Control of protein orientation on gold nanoparticles

W Lin, T Insley, MD Tuttle, L Zhu… - The Journal of …, 2015 - ACS Publications
Gold nanoparticles (Au NPs) have attracted much attention due to their potential
applications in nanomedicine. While numerous studies have quantified biomolecular …

Designing Functional Bionanoconstructs for Effective In Vivo Targeting

A Fleming, L Cursi, JA Behan, Y Yan, Z Xie… - Bioconjugate …, 2022 - ACS Publications
The progress achieved over the last three decades in the field of bioconjugation has
enabled the preparation of sophisticated nanomaterial–biomolecule conjugates, referred to …

Quantification of lipid corona formation on colloidal nanoparticles from lipid vesicles

X Zhang, AK Pandiakumar, RJ Hamers… - Analytical …, 2018 - ACS Publications
Formation of a protein corona around nanoparticles when immersed into biological fluids is
well-known; less studied is the formation of lipid coronas around nanoparticles. In many …

Environmentally toxic solid nanoparticles in noradrenergic and dopaminergic nuclei and cerebellum of metropolitan Mexico City children and young adults with neural …

L Calderón-Garcidueñas, A González-Maciel… - Toxics, 2022 - mdpi.com
Quadruple aberrant hyperphosphorylated tau, beta-amyloid, α-synuclein and TDP-43
neuropathology and metal solid nanoparticles (NPs) are documented in the brains of …

Dual-functional selenium nanoparticles bind to and inhibit amyloid β fiber formation in Alzheimer's disease

L Yang, J Sun, W Xie, Y Liu, J Liu - Journal of Materials Chemistry B, 2017 - pubs.rsc.org
Inhibition of amyloid β (Aβ) aggregation holds considerable promise as a therapeutic
strategy for Alzheimer's disease (AD). However, successful inhibition is hard to achieve due …

Drug delivery systems for imaging and therapy of Parkinson's disease

M Silindir Gunay, A Yekta Ozer… - Current …, 2016 - ingentaconnect.com
Background: Although a variety of therapeutic approaches are available for the treatment of
Parkinson's disease, challenges limit effective therapy. Among these challenges are delivery …

Protein adsorption to charged gold nanospheres as a function of protein deformability

JM Dennison, JM Zupancic, W Lin, JH Dwyer… - Langmuir, 2017 - ACS Publications
The corona that forms as protein adsorbs to gold nanospheres (AuNSs) is directly influenced
by the surface chemistry of the AuNS. Tools to predict adsorption outcomes are needed for …