The mucosal lining of the gut has co-evolved with a diverse microbiota over millions of
years, leading to the development of specialized mechanisms to actively limit the invasion of …

Helicobacter pylori (H. pylori) is one of the most common human pathogens, affecting half of
the world's population. Approximately 20% of the infected patients develop gastric ulcers or …

Summary The Helicobacter pylori (Hp) type IV secretion system (T4SS) forms needle-like
pili, whose binding to the integrin-β 1 receptor results in injection of the CagA oncoprotein …

Helicobacter pylori is the main pathogenic bacterium involved in chronic gastritis and peptic
ulcer and a class 1 carcinogen in gastric cancer. Current research focuses on the …

Gastrointestinal infections often induce epithelial damage that must be repaired for optimal
gut function. While intestinal stem cells are critical for this regeneration process [RC van der …

Outer membrane vesicles (OMVs) play an important role in the pathogenicity of Gram‐
negative bacteria. Campylobacter jejuni produces OMVs that trigger IL‐8, IL‐6, hBD‐3 and …

Gut microbiota plays an important role in the gut and have become a hotspot of recent
research interests. Commensal microbiota in gut exert a variety of effects on the host, from …

Helicobacter pylori is a highly successful human bacterium, which is exceptionally equipped
to persistently inhabit the human stomach. Colonization by this pathogen is associated with …

Breakdown of paracellular and vascular pathways and activated neuroimmune and
oxidative pathways was established in (deficit) schizophrenia. The aim of this study was to …

Infection with the protozoan parasite Cryptosporidium parvum (CP) causes
cryptosporidiosis, a widespread diarrhoeal disease. Impaired intestinal epithelial barrier …