The global burden of neurodegenerative disorders has increased substantially over the past
2 decades due to rising rates of population aging. Although neurodegenerative disorders …

Alzheimer's disease (AD) is a severe, chronic and progressive neurodegenerative disease
associated with memory and cognition impairment ultimately leading to death. It is the …

Dementia is a clinical syndrome wherein gradual decline of mental and cognitive
capabilities of an afflicted person takes place. Dementia is associated with various risk …

Ageing is an inevitable fundamental process for people and is their greatest risk factor for
neurodegenerative disease. The ageing processes bring changes in cells that can drive the …

Inflammaging is a term used to describe the tight relationship between low-grade chronic
inflammation and aging that occurs during physiological aging in the absence of evident …

Oxidative stress plays a critical role in various neurodegenerative diseases, thus alleviating
oxidative stress is a potential strategy for therapeutic intervention and/or prevention of …

Nitric oxide (NO) plays several key roles in the functionality of an organism, and it is usually
released in numerous organs and tissues. There are mainly three isoforms of the enzyme …

Glial cells (astrocytes, oligodendrocytes and microglia) are critical for the central nervous
system (CNS) in both physiological and pathological conditions. With this in mind, several …

Mitochondria are key cellular organelles that play crucial roles in the energy production and
regulation of cellular metabolism. Accumulating evidence suggests that mitochondrial …

Curcumin has been widely used to treat numerous diseases due to its antioxidant property.
The aim of the present study is to investigate the effect of curcumin on skeletal muscle …