Clinical applications of stem cell-derived exosomes
F Tan, X Li, Z Wang, J Li, K Shahzad… - Signal Transduction and …, 2024 - nature.com
Although stem cell-based therapy has demonstrated considerable potential to manage
certain diseases more successfully than conventional surgery, it nevertheless comes with …
certain diseases more successfully than conventional surgery, it nevertheless comes with …
Unraveling Endothelial Cell Migration: Insights into Fundamental Forces, Inflammation, Biomaterial Applications, and Tissue Regeneration Strategies
D Jerka, K Bonowicz, K Piekarska… - ACS Applied Bio …, 2024 - ACS Publications
Cell migration is vital for many fundamental biological processes and human pathologies
throughout our life. Dynamic molecular changes in the tissue microenvironment determine …
throughout our life. Dynamic molecular changes in the tissue microenvironment determine …
Tuning the extracellular vesicles membrane through fusion for biomedical applications
M Karmacharya, S Kumar, YK Cho - Journal of Functional Biomaterials, 2023 - mdpi.com
Membrane fusion is one of the key phenomena in the living cell for maintaining the basic
function of life. Extracellular vesicles (EVs) have the ability to transfer information between …
function of life. Extracellular vesicles (EVs) have the ability to transfer information between …
Advanced therapeutic medicinal products in bone and cartilage defects
The number of patients with functional loss of bone and cartilage tissue has shown an
increasing trend. Insufficient or inappropriate conventional treatments applied for trauma …
increasing trend. Insufficient or inappropriate conventional treatments applied for trauma …
Intra‐Articular Injection of Nanomaterials for the Treatment of Osteoarthritis: From Lubrication Function Restoration to Cell and Gene Therapy
Y Yang, H Zhang - Advanced Functional Materials, 2024 - Wiley Online Library
Osteoarthritis (OA), a prevalent joint disease affecting many people globally, presents
significant challenge in current treatments, which often only manage symptoms without …
significant challenge in current treatments, which often only manage symptoms without …
[HTML][HTML] Stem Cell-Based Acellular Therapy: Insight into Biogenesis, Bioengineering and Therapeutic Applications of Exosomes
The vast regenerative potential of stem cells has laid the foundation for stem cell-based
therapies. However, certain challenges limit the application of cell-based therapies. The …
therapies. However, certain challenges limit the application of cell-based therapies. The …
Bone and cartilage biology
R Nishimura - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent technical and conceptual advances in molecular and cellular biology have
dramatically advanced bone and cartilage biology. This progress has also improved our …
dramatically advanced bone and cartilage biology. This progress has also improved our …
[HTML][HTML] Downregulation of Gadd45β alleviates osteoarthritis by repressing lipopolysaccharide-induced fibroblast-like synoviocyte inflammation, proliferation and …
S Wu, W Guo, L Chen, X Lin, M Tang, C Lin… - International …, 2024 - Elsevier
Objective Gadd45β have a regulatory role in cellular inflammation, proliferation and
migration. However, the role of Gadd45β in synovial inflammation in osteoarthritis (OA) …
migration. However, the role of Gadd45β in synovial inflammation in osteoarthritis (OA) …
Therapeutic Effects of Mesenchymal Stem Cells Derived from Bone Marrow and Adipose Tissue in a Rat Model of Temporomandibular Osteoarthritis
S Khazeni, M Ghavimi, M Mesgari-Abbasi… - Journal of Oral …, 2024 - Elsevier
Objectives To examine the potential of intra-articular administration of mesenchymal stem
cells (MSCs) derived from bone marrow or adipose tissue to mitigate synovial inflammation …
cells (MSCs) derived from bone marrow or adipose tissue to mitigate synovial inflammation …