Simple and complex carbohydrates (glycans) have long been known to play major
metabolic, structural and physical roles in biological systems. Targeted microbial binding to …

During malignant transformation, glycosylation is heavily altered compared with healthy
tissue due to differential expression of glycosyltransferases, glycosidases and …

Cancer immunotherapy in the form of immune checkpoint inhibitors and cellular therapies
has improved the treatment and prognosis of many patients. Nevertheless, most cancers are …

A well known, epidemiologically reproducible risk factor for human carcinomas is the long-
term consumption of “red meat” of mammalian origin. Although multiple theories have …

A growing body of evidence supports crucial roles for glycans at various pathophysiological
steps of tumour progression. Glycans regulate tumour proliferation, invasion …

One of the most consistent epidemiological associations between diet and human disease
risk is the impact of red meat consumption (beef, pork, and lamb, particularly in processed …

The description of “serum sickness” more than a century ago in humans transfused with
animal sera eventually led to identification of a class of human antibodies directed against …

Cancer is a major cause of death in both developing and developed countries. Early
detection and efficient therapy can greatly enhance survival. Aberrant glycosylation has …

It has long been debated whether a little stress may be “good” for you. Extensive evidence
has now sufficiently accumulated demonstrating that low doses of a vast range of chemical …

Aberrant glycosylation is a key feature of malignant transformation and reflects epigenetic
and genetic anomalies among the multitude of molecules involved in glycan biosynthesis …