[HTML][HTML] Astrocytes: dissecting their diverse roles in amyotrophic lateral sclerosis and frontotemporal dementia

CF Valori, C Sulmona, L Brambilla, D Rossi - Cells, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are fatal
neurodegenerative disorders often co-occurring in the same patient, a feature that suggests …

Molecular and cellular mechanisms of selective vulnerability in neurodegenerative diseases

M Kampmann - Nature Reviews Neuroscience, 2024 - nature.com
The selective vulnerability of specific neuronal subtypes is a hallmark of neurodegenerative
diseases. In this Review, I summarize our current understanding of the brain regions and …

[HTML][HTML] Regulation of cortical hyperexcitability in amyotrophic lateral sclerosis: focusing on glial mechanisms

M Xie, PN Pallegar, S Parusel, AT Nguyen… - Molecular …, 2023 - Springer
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder
characterized by the loss of both upper and lower motor neurons, resulting in muscle …

Montelukast improves disease outcome in SOD1G93A female mice by counteracting oligodendrocyte dysfunction and aberrant glial reactivity

S Raffaele, N Nguyen, M Milanese… - British Journal of …, 2024 - Wiley Online Library
Abstract Background and Purpose Amyotrophic lateral sclerosis (ALS) is a fatal
neurodegenerative disorder characterized by progressive motor neuron (MN) loss and …