Chronic hepatitis B virus (HBV) infection is a common cause of liver disease globally, with a
disproportionately high burden in South-East Asia. Vaccines and nucleoside or nucleotide …

Representatives from academia, industry, regulatory agencies, and patient groups
convened in March 2019 with the primary goal of developing agreement on chronic hepatitis …

Hepatitis B virus (HBV) infection remains a global public health problem with changing
epidemiology due to several factors including vaccination policies and migration. This …

Background & Aims It has been proposed that serum hepatitis B core-related antigen
(HBcrAg) reflects intrahepatic covalently closed circular (ccc) DNA levels. However, the …

In the past 10 years, there has been a lot of enthusiasm surrounding the use of serum
hepatitis B surface antigen (HBsAg) quantification to predict disease activity and monitor …

Hepatitis B virus (HBV) infection is a major cause of acute and chronic liver disease and
associated morbidity and mortality worldwide. Vertical (mother-to-child) and horizontal early …

Wilson disease (WD) is an inherited disorder of hepatic copper metabolism with
considerable variation in clinical presentations, the most common ones being liver disease …

Chronic hepatitis B (CHB) is a major cause of liver-related morbidity and mortality.
Functional cure of CHB, defined as sustainable hepatitis B surface antigen (HBsAg) …

HBV deposits a covalently closed circular DNA form, called cccDNA, in the nucleus of
infected cells. As the central transcription template, the cccDNA minichromosome is a key …

Background & Aims One strategy to treat chronic hepatitis B virus (HBV) infection could be to
increase the functions of virus-specific T cells. We performed a multicenter phase 2 study to …