Throughout their evolutionary history, bacteria have faced diverse threats from other
microorganisms, including competing bacteria, bacteriophages and predators. In response …

Iron is an essential trace element for most organisms. A common way for bacteria to acquire
this nutrient is through the secretion of siderophores, which are secondary metabolites that …

Multitargeting compounds comprising activity on more than a single biological target have
gained remarkable relevance in drug discovery owing to the complexity of multifactorial …

The emergence of antimicrobial resistance is a significant public health issue worldwide,
particularly for healthcare-associated infections caused by carbapenem-resistant gram …

Sulfur plays a critical role for the development and maintenance of life on earth, which is
reflected by the wealth of primary metabolites, macromolecules, and cofactors bearing this …

Siderophores are small organic molecules produced by microorganisms under iron-limiting
conditions which enhance the uptake of iron to the microorganisms. In environment, the …

Iron is an essential nutrient for bacterial growth, replication, and metabolism. Humans store
iron bound to various proteins such as hemoglobin, haptoglobin, transferrin, ferritin, and …

Bacteria secrete small molecules known as siderophores to acquire iron from their
surroundings. For over 60 years, investigations into the bioinorganic chemistry of these …

Catechols are found in nature taking part in a remarkably broad scope of biochemical
processes and functions. Though not exclusively, such versatility may be traced back to …

A systematic analysis of all naturally-occurring glycosylated bacterial secondary metabolites
reported in the scientific literature up through early 2013 is presented. This comprehensive …