Drug-induced liver injury

RJ Andrade, N Chalasani, ES Björnsson… - Nature Reviews …, 2019 - nature.com
Drug-induced liver injury (DILI) is an adverse reaction to drugs or other xenobiotics that
occurs either as a predictable event when an individual is exposed to toxic doses of some …

Epilepsy in older people

A Sen, N Jette, M Husain, JW Sander - The Lancet, 2020 - thelancet.com
Globally, as populations age there will be challenges and opportunities to deliver optimal
health care to senior citizens. Epilepsy, a condition characterised by spontaneous recurrent …

GABAkines–Advances in the discovery, development, and commercialization of positive allosteric modulators of GABAA receptors

A Lippa, MM Poe, JL Smith, X Jin, X Ping… - Pharmacology & …, 2022 - Elsevier
Positive allosteric modulators of γ-aminobutyric acid-A (GABA A) receptors or GABAkines
have been widely used medicines for over 70 years for anxiety, epilepsy, sleep, and other …

Adverse drug reactions in primary care: a scoping review

H Khalil, C Huang - BMC health services research, 2020 - Springer
Background Medication-related adverse events, or adverse drug reactions (ADRs) are
harmful events caused by medication. ADRs could have profound effects on the patients' …

Mechanisms underlying aggressive behavior induced by antiepileptic drugs: focus on topiramate, levetiracetam, and perampanel

CC Hansen, H Ljung, E Brodtkorb… - Behavioural …, 2018 - Wiley Online Library
Antiepileptic drugs (AEDs) are effective against seizures, but their use is often limited by
adverse effects, among them psychiatric and behavioral ones including aggressive behavior …

Carbamazepine adverse drug reactions

I Fricke-Galindo, A LLerena, H Jung-Cook… - Expert review of …, 2018 - Taylor & Francis
Introduction: Carbamazepine (CBZ) is used for the treatment of epilepsy and other
neurological and psychiatric disorders. The occurrence of adverse reactions (ADRs) to CBZ …

Anti-seizure activity of African medicinal plants: The identification of bioactive alkaloids from the stem bark of Rauvolfia caffra using an in vivo zebrafish model

T Chipiti, AM Viljoen, ML Cordero-Maldonado… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Epilepsy is one of the major chronic diseases that does
not have a cure to date. Adverse drug reactions have been reported from the use of …

Fighting Epilepsy with Nanomedicines—Is This the Right Weapon?

M Matias, AO Santos, S Silvestre, G Alves - Pharmaceutics, 2023 - mdpi.com
Epilepsy is a chronic and complex condition and is one of the most common neurological
diseases, affecting about 50 million people worldwide. Pharmacological therapy has been …

[HTML][HTML] Drug-induced liver injury and prospect of cytokine based therapy; A focus on IL-2 based therapies

N Kumar, S Surani, G Udeani, S Mathew, S John… - Life Sciences, 2021 - Elsevier
Drug-induced liver injury (DILI) is one of the most frequent sources of liver failure and the
leading cause of liver transplant. Common non-prescription medications such as non …

Management of traumatic brain injury

JR Davanzo, EP Sieg, SD Timmons - Surgical Clinics, 2017 - surgical.theclinics.com
According to the Centers for Disease Control and Prevention, injury remains the leading
cause of death in the United States for all persons aged 1 to 44 years, is the third leading …