One excellent illustration of how a single gene abnormality may result in a spectrum of
disease incidence is the incredible phenotypic variety of β-thalassemia, which spans from …

Introduction: About 2% of the population in the world are carriers of the thalassemia gene.
Thalassemia is highly prevalent in Southern China, and traditional clinical testing methods …

Hemoglobinopathies are the most common single gene disorders (monogenic disorders) in
the world population. Due to specific position of Iran and the presence of multi-ethnic groups …

Thalassemia is one of the most common single gene disorders worldwide. Nearly 80 to 90
million with minor beta thalassemia and 60–70 thousand affected infants are born annually …

Objective The two most frequent hypochromic microcytic anemias are β-thalassemia minor
(BTM) and iron deficiency anemia (IDA). Several discrimination indices have been proposed …

Background Thalassemia is the most common monogenic disease in South-East of Iran.
Despite the 70% reduction in Iranian thalassemia cases after thalassemia control …

There is large variation in the molecular genetics and clinical features of
hemoglobinopathies in Iran. Studying structural variants of hemoglobin demonstrated that …

Objectives Thalassemia (thal) is the most single gene disorders in southeast of Iran. About
one quarter of total Iranian new thal cases were born in the Sistan and Balouchistan …

Low quality of life (QOL) is a feature that has been overlooked in thalassemia major (TM)
patients. Our aim was to assess QOL in school-aged TM patients in Zabol city and …

Background There currently is a lack of knowledge about the long-term survival of patients
with beta thalassemia (BT), particularly in regions with low incidence of the disease. The aim …