While the Staudinger reaction has first been described a hundred years ago in 1919, the
ligation reaction became one of the most important and efficient bioconjugation techniques …

Bottom‐up tissue engineering is a promising approach for designing modular biomimetic
structures that aim to recapitulate the intricate hierarchy and biofunctionality of native human …

Polysaccharide chemistry is enjoying accelerating development thanks to advances in
synthetic techniques, biochemistry and solvents, which enable polysaccharide materials to …

Encapsulating living cells within multilayer functional shells is a crucial extension of cellular
functions and a further development of cell surface engineering. In the last decade, cell …

Encapsulation of islets of Langerhans may represent a way to transplant islets in the
absence of immunosuppression. Traditional methods for encapsulation lead to diffusional …

Treating many chronic diseases will require a tight, minute-to-minute regulation of
therapeutic molecules that is currently not achievable with most pharmaceutical therapies …

Bioorthogonal phosphines were introduced in the context of the Staudinger ligation over 20
years ago. Since that time, phosphine probes have been used in myriad applications to tag …

Cell therapies are emerging as a promising new therapeutic modality in medicine,
generating effective treatments for previously incurable diseases. Clinical success of cell …

A cure for type 1 diabetes (T1D) would help millions of people worldwide but remains
elusive to date. Tolerogenic vaccines and β-cell replacement therapy are complementary …

Nanotechnology in diabetes research has facilitated the development of novel glucose
measurement and insulin delivery modalities which hold the potential to dramatically …