Potential diagnostic biomarkers for schizophrenia

W Yue, H Huang, J Duan - Medical Review, 2022 - degruyter.com
Schizophrenia (SCH) is a complex and severe mental disorder with high prevalence,
disability, mortality and carries a heavy disease burden, the lifetime prevalence of SCH is …

The Interrelation between Interleukin-2 and Schizophrenia

Y Huang, X Zhang, N Zhou - Brain Sciences, 2022 - mdpi.com
Interleukin-2 (IL-2) is a growth factor that regulates T-cell autocrine secretion and has long
been considered to be closely related to immune response. With the advance in …

Rationale for Adjunctive Treatment Targeting Multiple Mechanisms in Schizophrenia

BJ Kinon, S Leucht, C Tamminga, A Breier… - The Journal of …, 2024 - psychiatrist.com
Importance: Schizophrenia is a complex syndrome with taxing symptoms and for which
treatment challenges remain. Current dopamine D 2 receptor–blocking antipsychotics have …

Recent applications of positron emission tomographic (PET) imaging in psychiatric drug discovery

L Zimmer - Expert Opinion on Drug Discovery, 2024 - Taylor & Francis
Introduction Psychiatry is one of the medical disciplines that suffers most from a lack of
innovation in its therapeutic arsenal. Many failures in drug candidate trials can be explained …

Deciphering the landscape of lncRNA-driven ceRNA network in schizophrenia etiology

A Mukhopadhyay, P Singh, R Dohare… - Egyptian Journal of …, 2024 - Springer
Background The unifying hypothesis of competing endogenous RNA (ceRNA) wherein
crosstalk between coding (mRNAs) and long non-coding RNAs (lncRNAs) via microRNA …

Plasma metabolomics reveals the intervention mechanism of different types of exercise on chronic unpredictable mild stress-induced depression rat model

X Liu, B Zhang, J Tian, Y Han - Metabolic Brain Disease, 2024 - Springer
Objective To study the effects of different types of exercise on the plasma metabolomics of
chronic unpredictable mild stress (CUMS)-induced depressed rats based on 1H-NMR …