Obesity, particularly severe obesity is capable of producing hemodynamic alterations that
predispose to changes in cardiac morphology and ventricular function. These include …

Obesity is a major risk factor for heart disease. In the face of obesity's growing prevalence, it
is important for physicians to be aware of emerging research of novel mechanisms through …

Objectives: This study was designed to determine the effects of obesity on left ventricular
(LV) structure and function in young obese women. Background: Severe prolonged obesity …

Objective: To evaluate whether or not “uncomplicated” obesity (without associated
comorbidities) is really associated with cardiac abnormalities. Research Methods and …

Objective: A massive amount of fat tissue, as that observed in obese subjects with BMI over
50 kg/m2, could affect cardiac morphology and performance, but few data on this issue are …

Cardiovascular disease is a major cause of mortality and morbidity in individuals with
obesity, type 2 diabetes and the metabolic syndrome. The mechanisms for this are partially …

Protein kinase A (PKA) is a multi-unit protein kinase that mediates signal transduction of G-
protein-coupled receptors through its activation by adenyl cyclase (AC)-mediated cAMP. The …

Obesity is a growing worldwide problem and the prevalence of heart failure is also on the
rise. Obesity itself is an independent risk factor for the development of heart failure and the …

Background: Obesity and hypertension (HT) are well known cardiac risk factors. Our goal
was to show that even if arterial blood pressure (BP) measurements of obese adolescents …

We sought to examine the influence of adiposity in age-associated changes in the left
ventricle (LV) in a cohort of 113 healthy men, aged 20–79 yr, by measuring LV structure and …