Melanosomes are melanocyte-specific organelles that protect cells from ultraviolet (UV)-
induced deoxyribonucleic acid damage through the production and accumulation of melanin …

The skin forms the barrier to the environment. Maintenance of this barrier during aging
requires orchestrated responses to variable types of stress, the continuous renewal of the …

Cancer‐associated fibroblasts (CAFs) as a predominant cell component in the tumour
microenvironment (TME) play an essential role in tumour progression. Our earlier studies …

Endoplasmic reticulum (ER) stress is thought to activate autophagy via unfolded protein
response (UPR)-mediated transcriptional up-regulation of autophagy machinery …

Aggregation of α-Synuclein is central to the pathogenesis of Parkinson's disease (PD).
However, these α-Synuclein inclusions are not only present in brain, but also in gut …

Primary dysfunction of autophagy due to Mendelian defects affecting core components of the
autophagy machinery or closely related proteins have recently emerged as an important …

Melanosomes are specialized membrane-bound organelles that synthesize and organize
melanin, ultimately providing color to the skin, hair, and eyes. Disorders in melanogenesis …

Autophagy is a vital process for cell survival and it preserves homeostasis by recycling or
disassembling unnecessary or dysfunctional cellular constituents. Autophagy ameliorates …

Blue light, a high-energy radiation in the visible light spectrum, was recently reported to
induce skin pigmentation. In this study, we investigated the involvement of TRPV1-mediated …

Mycotoxins are toxic metabolites produced by fungal species that commonly present in the
global environment, especially in cereals and animal forages. The changing global …