Highlights•Drosophila AMPs contribute to host defense, notably against Gram-negative
bacteria.•Certain AMPs show exquisite specifity against certain pathogens.•Certain AMPs …

The peripheral nervous and immune systems are traditionally thought of as serving separate
functions. The line between them is, however, becoming increasingly blurred by new …

Background The amyloid β-protein (Aβ) is believed to be the key mediator of Alzheimer's
disease (AD) pathology. Aβ is most often characterized as an incidental catabolic byproduct …

Antimicrobial peptides of multicellular organisms were first characterized in the 1980s by
investigators who felt that known systems of immunity could not explain what they observed …

As the key components of innate immunity, human host defense antimicrobial peptides and
proteins (AMPs) play a critical role in warding off invading microbial pathogens. In addition …

This review focuses on the role of the peripheral nervous system in cutaneous biology and
disease. During the last few years, a modern concept of an interactive network between …

Background: Increasing evidence suggests that thyroid hormones, L-thyroxine (T4) and 3,
3′, 5-triiodo-L-thyronine (T3), are modulators of the immune response. In monocytes …

Evolution has yielded multiple complex and complementary mechanisms to detect
environmental danger and protect tissues from damage. The nervous system rapidly …

Synthetic macromolecular antimicrobials have shown efficacy in the treatment of multidrug
resistant (MDR) pathogens. These synthetic macromolecules, inspired by Nature's …

There are some∼ 1,100 known antimicrobial peptides (AMPs), which permeabilize
microbial membranes but have diverse sequences. Here, we develop a support vector …