Pretreating and normalizing metabolomics data for statistical analysis
J Sun, Y Xia - Genes & Diseases, 2024 - Elsevier
Metabolomics as a research field and a set of techniques is to study the entire small
molecules in biological samples. Metabolomics is emerging as a powerful tool generally for …
molecules in biological samples. Metabolomics is emerging as a powerful tool generally for …
[HTML][HTML] Metabolic crosstalk in the breast cancer microenvironment
During tumorigenesis, breast tumour cells undergo metabolic reprogramming, which
generally includes enhanced glycolysis, tricarboxylic acid cycle activity, glutaminolysis and …
generally includes enhanced glycolysis, tricarboxylic acid cycle activity, glutaminolysis and …
NMR-based metabolomics in human disease diagnosis: applications, limitations, and recommendations
Metabolomics is a dynamic and emerging research field, similar to proteomics,
transcriptomics and genomics in affording global understanding of biological systems. It is …
transcriptomics and genomics in affording global understanding of biological systems. It is …
[HTML][HTML] Triple-negative breast cancer: present challenges and new perspectives
F Podo, LMC Buydens, H Degani, R Hilhorst, E Klipp… - Molecular …, 2010 - Elsevier
Triple-negative breast cancers (TNBC), characterized by absence of estrogen receptor (ER),
progesterone receptor (PR) and lack of overexpression of human epidermal growth factor …
progesterone receptor (PR) and lack of overexpression of human epidermal growth factor …
Focus on the glycerophosphocholine pathway in choline phospholipid metabolism of cancer
Activated choline metabolism is a hallmark of carcinogenesis and tumor progression, which
leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …
leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …
Early detection of recurrent breast cancer using metabolite profiling
VM Asiago, LZ Alvarado, N Shanaiah, GAN Gowda… - Cancer research, 2010 - AACR
We report on the development of a monitoring test for recurrent breast cancer, using
metabolite-profiling methods. Using a combination of nuclear magnetic resonance (NMR) …
metabolite-profiling methods. Using a combination of nuclear magnetic resonance (NMR) …
Performance evaluation and online realization of data-driven normalization methods used in LC/MS based untargeted metabolomics analysis
In untargeted metabolomics analysis, several factors (eg, unwanted experimental &
biological variations and technical errors) may hamper the identification of differential …
biological variations and technical errors) may hamper the identification of differential …
Omics technologies improving breast cancer research and diagnostics
A Orsini, C Diquigiovanni, E Bonora - International Journal of Molecular …, 2023 - mdpi.com
Breast cancer (BC) has yielded approximately 2.26 million new cases and has caused
nearly 685,000 deaths worldwide in the last two years, making it the most common …
nearly 685,000 deaths worldwide in the last two years, making it the most common …
Metabolic characterization of triple negative breast cancer
MD Cao, S Lamichhane, S Lundgren, A Bofin, H Fjøsne… - BMC cancer, 2014 - Springer
Background The aims of this study were to characterize the metabolite profiles of triple
negative breast cancer (TNBC) and to investigate the metabolite profiles associated with …
negative breast cancer (TNBC) and to investigate the metabolite profiles associated with …
A distinct metabolic signature of human colorectal cancer with prognostic potential
Purpose: Metabolic phenotyping has provided important biomarker findings, which,
unfortunately, are rarely replicated across different sample sets due to the variations from …
unfortunately, are rarely replicated across different sample sets due to the variations from …