Fertility preservation in boys: recent developments and new insights

E Goossens, K Jahnukainen, RT Mitchell… - Human …, 2020 - academic.oup.com
BACKGROUND Infertility is an important side effect of treatments used for cancer and other
non-malignant conditions in males. This may be due to the loss of spermatogonial stem cells …

A European perspective on testicular tissue cryopreservation for fertility preservation in prepubertal and adolescent boys

HM Picton, C Wyns, RA Anderson… - Human …, 2015 - academic.oup.com
STUDY QUESTION What clinical practices, patient management strategies and
experimental methods are currently being used to preserve and restore the fertility of …

Autologous grafting of cryopreserved prepubertal rhesus testis produces sperm and offspring

AP Fayomi, K Peters, M Sukhwani, H Valli-Pulaski… - Science, 2019 - science.org
Testicular tissue cryopreservation is an experimental method to preserve the fertility of
prepubertal patients before they initiate gonadotoxic therapies for cancer or other conditions …

[HTML][HTML] Fertility preservation in patients undergoing gonadotoxic therapy or gonadectomy: a committee opinion

Practice Committee of the American Society for … - Fertility and …, 2019 - Elsevier
Patients preparing to undergo gonadotoxic medical therapy, radiation therapy, or
gonadectomy should be provided with prompt counseling regarding available options for …

[HTML][HTML] Spermatogonial stem cells for in vitro spermatogenesis and in vivo restoration of fertility

F Ibtisham, A Honaramooz - Cells, 2020 - mdpi.com
Spermatogonial stem cells (SSCs) are the only adult stem cells capable of passing genes
onto the next generation. SSCs also have the potential to provide important knowledge …

Options for fertility preservation in prepubertal boys

C Wyns, M Curaba, B Vanabelle… - Human reproduction …, 2010 - academic.oup.com
BACKGROUND Fertility in adult life may be severely impaired by gonadotoxic therapies. For
young boys who do not yet produce spermatozoa, cryopreservation of immature testicular …

[HTML][HTML] Experimental methods to preserve male fertility and treat male factor infertility

K Gassei, KE Orwig - Fertility and sterility, 2016 - Elsevier
Infertility is a prevalent condition that has insidious impacts on the infertile individuals, their
families, and society, which extend far beyond the inability to have a biological child …

[HTML][HTML] Stem cells in veterinary medicine

LA Fortier, AJ Travis - Stem cell research & therapy, 2011 - Springer
The stem cell field in veterinary medicine continues to evolve rapidly both experimentally
and clinically. Stem cells are most commonly used in clinical veterinary medicine in …

Long-term spermatogonial survival in cryopreserved and xenografted immature human testicular tissue

C Wyns, A Van Langendonckt, FX Wese… - Human …, 2008 - academic.oup.com
BACKGROUND Preservation of the male germ line in prepubertal boys undergoing
gonadotoxic treatment is a crucial consideration in terms of their future quality of life. As …

Male fertility preservation and restoration strategies for patients undergoing gonadotoxic therapies

KTD Tran, H Valli-Pulaski, A Colvin… - Biology of …, 2022 - academic.oup.com
Medical treatments for cancers or other conditions can lead to permanent infertility. Infertility
is an insidious disease that impacts not only the ability to have a biological child but also the …