Spinal cord stimulation for spasticity: historical approaches, current status, and future directions

SJ Nagel, S Wilson, MD Johnson, A Machado… - … : Technology at the …, 2017 - Elsevier
Introduction Millions of people worldwide suffer with spasticity related to irreversible damage
to the brain or spinal cord. Typical antecedent events include stroke, traumatic brain injury …

High-frequency spinal cord stimulation for chronic pain: pre-clinical overview and systematic review of controlled trials

MC Bicket, RY Dunn, SU Ahmed - Pain medicine, 2016 - academic.oup.com
Objective. To assess the evidence base for high-frequency spinal cord stimulation (HFSCS).
HFSCS has the potential to provide paresthesia-free pain relief for patients with chronic …

Real-world outcomes using a spinal cord stimulation device capable of combination therapy for chronic pain: a European, multicenter experience

JW Kallewaard, JF Paz-Solis, P De Negri… - Journal of Clinical …, 2021 - mdpi.com
Given the differing mechanisms thought to underlie therapeutic sub-and supra-perception-
based neurostimulative modalities, Spinal Cord Stimulation (SCS) systems designed for …

Brain-computer-spinal interface restores upper limb function after spinal cord injury

S Samejima, A Khorasani… - … on Neural Systems …, 2021 - ieeexplore.ieee.org
Brain-computer interfaces (BCIs) are an emerging strategy for spinal cord injury (SCI)
intervention that may be used to reanimate paralyzed limbs. This approach requires …

Bioheat model of spinal column heating during high-density spinal cord stimulation

AL Zannou, N Khadka, M Bikson - Neuromodulation: Technology at the …, 2023 - Elsevier
Introduction High-density (HD) spinal cord stimulation (SCS) delivers higher charge per time
by increasing frequency and/or pulse duration, thus increasing stimulation energy …

Fiber threshold accommodation as a mechanism of burst and high-frequency spinal cord stimulation

JE Arle, L Mei, KW Carlson - Neuromodulation: Technology at the Neural …, 2020 - Elsevier
Objectives Burst and high-frequency spinal cord stimulation (SCS), in contrast to low-
frequency stimulation (LFS,< 200 Hz), reduce neuropathic pain without the side effect of …

Ovine model of neuropathic pain for assessing mechanisms of spinal cord stimulation therapy via dorsal horn recordings, von Frey filaments, and gait analysis

CG Reddy, JW Miller, KO Abode-Iyamah… - Journal of pain …, 2018 - Taylor & Francis
Background It is becoming increasingly important to understand the mechanisms of spinal
cord stimulation (SCS) in alleviating neuropathic pain as novel stimulation paradigms arise …

A scoping review of novel spinal cord stimulation modes for complex regional pain syndrome

Y Hoydonckx, M Costanzi, A Bhatia - Canadian Journal of Pain, 2019 - Taylor & Francis
Background Paresthesia-based spinal cord stimulation (PB-SCS) is used for the treatment of
complex regional pain syndrome (CRPS), but many patients are refractory to PB-SCS or …

Higher-order power harmonics of pulsed electrical stimulation modulates corticospinal contribution of peripheral nerve stimulation

CF Chen, M Bikson, LW Chou, C Shan, N Khadka… - Scientific reports, 2017 - nature.com
It is well established that electrical-stimulation frequency is crucial to determining the scale
of induced neuromodulation, particularly when attempting to modulate corticospinal …

Soleus H-reflex modulation following transcutaneous high-and low-frequency spinal stimulation in healthy volunteers

D Serrano-Muñoz, J Gómez-Soriano… - Journal of …, 2019 - Elsevier
The main aim of this work was to investigate the difference in the excitability of the soleus H-
reflex in healthy volunteers following spinal transcutaneous electrical nerve stimulation …