Niacin (vitamin B3) is an essential nutrient that treats pellagra, and prior to the advent of
statins, niacin was commonly used to counter dyslipidemia. Recent evidence has posited …

Flushing is a typical physiological reaction to high emotional reactions. It is characterized by
cutaneous vasodilation and a feeling of warmth and skin redness, especially in the face …

Non-covalent interactions in bio-macromolecules are individually weak but collectively
important. How they take a concerted action in a complex biochemical reaction network to …

Niacin is an important vitamin (B3) that can be used in gram doses to positively modify
pathogenetically relevant lipid disorders: elevated LDL cholesterol, elevated non-HDL …

The feasibility of bispectral imaging photoplethysmography (iPPG) system for clinical
assessment of cutaneous microcirculation at two different depths is proposed. The iPPG …

Both a silent resident phosphatidylinositol lipid and a “hot” vanilloid agonist capsaicin or
resiniferatoxin have been shown to share the same inter-subunit binding pocket between a …

TRPV ion channels are directly activated by sensory stimuli and participate in thermo-,
mechano-and chemo-sensation. They are also hypothesized to respond to endogenous …

Nicotinic acid (NA) activates hydroxycarboxylic acid receptor 2 (HCA2), and it is widely used
in treating dyslipidaemias. Since its side effects include skin dryness, whereas its deficiency …

Context Nicotinic acid and nicotinamide are soluble compounds of the vitamin B group,
widely used to regulate the lipid profile in hyperlipidemic individuals. Higher doses of …

Background: Cancer has become the second leading cause of death worldwide. Despite of
the availability of significant number of anticancer agents, cancer is still incurable especially …