Determinants of innate immunity in visceral leishmaniasis and their implication in vaccine development
G Volpedo, T Pacheco-Fernandez… - Frontiers in …, 2021 - frontiersin.org
Leishmaniasis is endemic to the tropical and subtropical regions of the world and is
transmitted by the bite of an infected sand fly. The multifaceted interactions between …
transmitted by the bite of an infected sand fly. The multifaceted interactions between …
Arginase and its mechanisms in Leishmania persistence
G Pessenda, JS da Silva - Parasite immunology, 2020 - Wiley Online Library
Leishmaniasis is a neglected infectious disease with clinical presentations ranging from
asymptomatic or mild symptoms to chronic infection and eventual death. The mechanisms of …
asymptomatic or mild symptoms to chronic infection and eventual death. The mechanisms of …
Determinants of Unresponsiveness to Treatment in Cutaneous Leishmaniasis: A Focus on Anthroponotic Form Due to Leishmania tropica
Cutaneous leishmaniasis (CL) is a curable disease; however, due to various risk factors,
unresponsiveness to CL treatments is inevitable. The treatment of CL has been firmly …
unresponsiveness to CL treatments is inevitable. The treatment of CL has been firmly …
Antileishmanial potentials of azacitidine and along with meglumine antimoniate on Leishmania major: In silico prediction and in vitro analysis
This study aimed to investigate the in vitro and in silico antileishmanial activity of azacitidine
(AZA) on Leishmania major promastigotes and amastigotes. The in silico method was used …
(AZA) on Leishmania major promastigotes and amastigotes. The in silico method was used …
The potential role of nicotinamide on Leishmania tropica: An assessment of inhibitory effect, cytokines gene expression and arginase profiling
Leishmaniasis represents a major health concern worldwide which has no effective
treatment modality. Nicotinamide (NAm) has been used for a wide range of applications from …
treatment modality. Nicotinamide (NAm) has been used for a wide range of applications from …
Global Dilemma and Needs Assessment Toward Achieving Sustainable Development Goals in Controlling Leishmaniasis
M Bamorovat, I Sharifi, A Khosravi… - Journal of Epidemiology …, 2024 - Springer
Leishmaniasis is a disease of poverty that imposes a devastating medical, social, and
economic burden on over 1 billion people nationwide. To date, no in-depth study to analyze …
economic burden on over 1 billion people nationwide. To date, no in-depth study to analyze …
TLR-mediated host immune response to parasitic infectious diseases
MM Aguirre-García, A Rojas-Bernabé… - Toll-like …, 2020 - books.google.com
Toll-like receptors (TLRs) are important for the host immune response to a variety of
pathogens, including bacteria, viruses, fungi, and parasites. These receptors become …
pathogens, including bacteria, viruses, fungi, and parasites. These receptors become …
The Effect of Naja naja oxiana Snake Venom Against Leishmania tropica Confirmed by Advanced Assays
Purpose The aim of this study was to explore the activity of Naja naja oxiana venom on
Leishmania tropica and its modes of action. Methods Different fractions of Naja naja oxiana …
Leishmania tropica and its modes of action. Methods Different fractions of Naja naja oxiana …
Induction of TLR5, IRAK1, and NF-κB expression by Trichomonas vaginalis in cervical cancer cell (HeLa) and normal human vaginal epithelial cell (HVECs) lines
Introduction: Trichomoniasis is the most common non-viral sexually transmitted infection that
increases the risk of cervical cancer. Trichomonas vaginalis (T. vaginalis) can regulate the …
increases the risk of cervical cancer. Trichomonas vaginalis (T. vaginalis) can regulate the …
Arginase/nitric oxide modifications using live non-pathogenic Leishmania tarentolae as an effective delivery system inside the mammalian macrophages
A Badirzadeh, H Montakhab-Yeganeh… - Journal of Parasitic …, 2021 - Springer
Recombinant live delivery system based on chemokine IFN-γ-inducible protein-10 kDa
(CXCL 10 or IP-10), as a suitable immunotherapy tool, have been used for the treatment of …
(CXCL 10 or IP-10), as a suitable immunotherapy tool, have been used for the treatment of …