Engineering of specific single-module nonribosomal peptide synthetases of the RXP type for the production of defined peptides

X Cai, L Zhao, HB Bode - ACS synthetic biology, 2022 - ACS Publications
Rhabdopeptide/xenortide-like peptide (RXP) nonribosomal peptide synthetases (NRPSs)
derived from entomophathogenic Xenorhabdus and Photorhabdus bacteria often produce …

High-resolution structures of a siderophore-producing cyclization domain from Yersinia pestis offer a refined proposal of substrate binding

AD Gnann, Y Xia, J Soule, C Barthélemy… - Journal of Biological …, 2022 - ASBMB
Nonribosomal peptide synthetase heterocyclization (Cy) domains generate biologically
important oxazoline/thiazoline groups found in natural products, including pharmaceuticals …

Studies of a siderophore-producing cyclization domain: A refined proposal of substrate binding

AD Gnann, Y Xia, J Soule, C Barthélemy, J Mawani… - bioRxiv, 2022 - biorxiv.org
Nonribosomal peptide synthetase (NRPS) heterocyclization (Cy) domains generate
biologically important ox-/thiazoline modifications in natural products, including in …

[图书][B] Understanding oxidation and dehydration modifications in nonribosomal peptide synthesis

CM Fortinez - 2021 - search.proquest.com
Nonribosomal peptide synthetases (NRPSs) are elegant megaenzymes responsible for
producing an array of bioactive secondary metabolites, useful as agricultural agents and …