Statin intolerance–an attempt at a unified definition. Position paper from an International Lipid Expert Panel: This paper is also published in parallel in Archives of …
Statins are one of the most commonly prescribed drugs in clinical practice. They are usually
well tolerated and effectively prevent cardiovascular events. Most adverse effects associated …
well tolerated and effectively prevent cardiovascular events. Most adverse effects associated …
Whole‐body endothermy: ancient, homologous and widespread among the ancestors of mammals, birds and crocodylians
The whole‐body (tachymetabolic) endothermy seen in modern birds and mammals is long
held to have evolved independently in each group, a reasonable assumption when it was …
held to have evolved independently in each group, a reasonable assumption when it was …
Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals
The role of skeletal muscle in nonshivering thermogenesis (NST) is not well understood.
Here we show that sarcolipin (Sln), a newly identified regulator of the sarco/endoplasmic …
Here we show that sarcolipin (Sln), a newly identified regulator of the sarco/endoplasmic …
Cellular bioenergetics as a target for obesity therapy
Obesity develops when energy intake exceeds energy expenditure. Although most current
obesity therapies are focused on reducing calorific intake, recent data suggest that …
obesity therapies are focused on reducing calorific intake, recent data suggest that …
[PDF][PDF] Skeletal muscle thermogenesis and its role in whole body energy metabolism
M Periasamy, JL Herrera… - Diabetes & metabolism …, 2017 - synapse.koreamed.org
Obesity and diabetes has become a major epidemic across the globe. Controlling obesity
has been a challenge since this would require either increased physical activity or reduced …
has been a challenge since this would require either increased physical activity or reduced …
Thermal facial image analyses reveal quantitative hallmarks of aging and metabolic diseases
Although human core body temperature is known to decrease with age, the age
dependency of facial temperature and its potential to indicate aging rate or aging-related …
dependency of facial temperature and its potential to indicate aging rate or aging-related …
The role of skeletal‐muscle‐based thermogenic mechanisms in vertebrate endothermy
LA Rowland, NC Bal, M Periasamy - Biological Reviews, 2015 - Wiley Online Library
Thermogenesis is one of the most important homeostatic mechanisms that evolved during
vertebrate evolution. Despite its importance for the survival of the organism, the mechanistic …
vertebrate evolution. Despite its importance for the survival of the organism, the mechanistic …
Genetically encoded fluorescent thermosensors visualize subcellular thermoregulation in living cells
S Kiyonaka, T Kajimoto, R Sakaguchi, D Shinmi… - Nature …, 2013 - nature.com
In mammals and birds, thermoregulation to conserve body temperature is vital to life.
Multiple mechanisms of thermogeneration have been proposed, localized in different …
Multiple mechanisms of thermogeneration have been proposed, localized in different …
Intracellular thermometry with fluorescent sensors for thermal biology
K Okabe, R Sakaguchi, B Shi, S Kiyonaka - Pflügers Archiv-European …, 2018 - Springer
Temperature influences the activities of living organisms at various levels. Cells not only
detect environmental temperature changes through their unique temperature-sensitive …
detect environmental temperature changes through their unique temperature-sensitive …
Uncoupling of sarcoendoplasmic reticulum calcium ATPase pump activity by sarcolipin as the basis for muscle non-shivering thermogenesis
NC Bal, M Periasamy - Philosophical Transactions of the …, 2020 - royalsocietypublishing.org
Thermogenesis in endotherms relies on both shivering and non-shivering thermogenesis
(NST). The role of brown adipose tissue (BAT) in NST is well recognized, but the role of …
(NST). The role of brown adipose tissue (BAT) in NST is well recognized, but the role of …