[HTML][HTML] From fundamentals in calibration to modern methodologies: a tutorial for small molecules quantification in liquid chromatography–mass spectrometry …

G Visconti, J Boccard, M Feinberg, S Rudaz - Analytica chimica acta, 2023 - Elsevier
Over the last two decades, liquid chromatography coupled to mass-spectrometry (LC‒MS)
has become the gold standard to perform qualitative and quantitative analyses of small …

[HTML][HTML] Clinical utility of laboratory developed mass spectrometry assays for steroid hormone testing

D French - Journal of Mass Spectrometry and Advances in the …, 2023 - Elsevier
It has long been recognized that immunoassays cannot accurately quantify steroid
hormones such as testosterone, estradiol, and aldosterone in certain patient populations …

Classic and 11-oxygenated androgens in serum and saliva across adulthood: a cross-sectional study analyzing the impact of age, body mass index, and diurnal and …

L Schiffer, P Kempegowda, AJ Sitch… - European Journal of …, 2023 - academic.oup.com
Objective 11-oxygenated androgens significantly contribute to the circulating androgen pool.
Understanding the physiological variation of 11-oxygenated androgens and their …

[HTML][HTML] Straightforward quantification of endogenous steroids with liquid chromatography–tandem mass spectrometry: Comparing calibration approaches

G Visconti, M De Figueiredo, O Salamin… - … of Chromatography B, 2023 - Elsevier
Different calibration strategies are used in liquid chromatography hyphenated to mass
spectrometry (LC-MS) bioanalysis. Currently, the surrogate matrix and surrogate analyte …

[HTML][HTML] An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the …

J Taibon, T Santner, N Singh, SC Ibrahim… - Clinical Chemistry and …, 2023 - degruyter.com
Objectives An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC
MS/MS)-based candidate reference measurement procedure (RMP) for aldosterone …

[HTML][HTML] Comprehensive plasma steroidomics reveals subtle alterations of systemic steroid profile in patients at different stages of prostate cancer disease

S Girel, PA Markin, E Tobolkina, J Boccard… - Scientific Reports, 2024 - nature.com
The steroid submetabolome, or steroidome, is of particular interest in prostate cancer (PCa)
as the dependence of PCa growth on androgens is well known and has been routinely …

Developments in on-line, post separation sample manipulation in the last 22 years: pharmaceutical and biomedical applications

A Tsiasioti, PD Tzanavaras - Journal of Pharmaceutical and Biomedical …, 2023 - Elsevier
On-line post separation sample manipulation is a powerful approach increasing the
sensitivity and selectivity in chemical analysis. Post separation sample manipulation …

[HTML][HTML] Development of a generic approach for monitoring leachable compounds in hospital pharmacy-prepared prefilled plastic packaging by ultrahigh-performance …

W Bello, J Pezzatti, M Berger-Gryllaki, S Rudaz… - … of Pharmaceutical and …, 2023 - Elsevier
Prefilled plastic packaging is time-and cost-effective in hospital pharmacy because it
prevents waste, preparation errors, dosage errors, microbial contamination and accidents …

[HTML][HTML] Simultaneous Measurement of Cortisol, Cortisone, Dexamethasone and Additional Exogenous Corticosteroids by Rapid and Sensitive LC–MS/MS Analysis

F Ponzetto, M Parasiliti-Caprino, F Settanni, A Nonnato… - Molecules, 2022 - mdpi.com
The simultaneous measurement of dexamethasone and cortisol has proven the ability to
increase the diagnostic performance of the overnight dexamethasone-suppression test …

Multitargeted Internal Calibration for the Quantification of Chronic Kidney Disease-Related Endogenous Metabolites Using Liquid Chromatography–Mass …

G Visconti, M de Figueiredo, O Strassel… - Analytical …, 2023 - ACS Publications
Accurate quantitative analysis in liquid chromatography–mass spectrometry (LC–MS)
benefits from calibration curves generated in the same matrix as the study sample. In the …