Recent developments in gene therapy research in India

R Selot, A Ghosh - Journal of Biosciences, 2024 - Springer
Inherited genetic disorders are progressive in nature and lead to organ dysfunction or death
in severe cases. At present, there are no permanent treatment options for> 95% of inherited …

Restoration of corneal epithelial barrier function: a possible target for corneal neovascularization

S Shen, Y Zhang - The Ocular Surface, 2024 - Elsevier
Corneal neovascularization (CoNV) is the second leading common cause of vision
impairment worldwide and is a blinding pathological alteration brought on by ocular trauma …

[HTML][HTML] Ocular Pathology and Genetics: Transformative Role of Artificial Intelligence (AI) in Anterior Segment Diseases

P Venkatapathappa, A Sultana, KS Vidhya, R Mansour… - Cureus, 2024 - ncbi.nlm.nih.gov
Artificial intelligence (AI) has become a revolutionary influence in the field of ophthalmology,
providing unparalleled capabilities in data analysis and pattern recognition. This narrative …

[HTML][HTML] Current Advances in Regenerative Strategies for Dry Eye Diseases: A Comprehensive Review

B Bhujel, SH Oh, CM Kim, YJ Yoon, HS Chung, EA Ye… - Bioengineering, 2023 - mdpi.com
Dry eye disease (DED) is an emerging health issue affecting millions of individuals annually.
Ocular surface disorders, such as DED, are characterized by inflammation triggered by …

Suppressing Pro-Apoptotic Proteins by siRNA in Corneal Endothelial Cells Protects against Cell Death

S Staehlke, S Mahajan, D Thieme, P Trosan… - Biomedicines, 2024 - mdpi.com
Corneal endothelial cells (CE) are critical for the cornea's transparency. For severe corneal
damage, corneal tissue transplantation is the most promising option for restoring vision …

[HTML][HTML] Gene therapy for retinal diseases: From genetics to treatment

A Khaparde, GP Mathias… - Indian Journal of …, 2024 - journals.lww.com
The gene therapy approach for retinal disorders has been considered largely over the last
decade owing to the favorable outcomes of the US Food and Drug Administration-approved …

[HTML][HTML] Advancements in keratoplasty: Exploring newer techniques and imaging modalities for enhanced surgical outcomes

S Aggarwal, M Kumari, N Bhatnagar - Saudi Journal of …, 2024 - journals.lww.com
Keratoplasty, the transplantation of corneal tissue, is a well-established surgical procedure
for the treatment of various corneal diseases. Over the years, advancements in keratoplasty …