Isolation of circulating tumor cells

JF Edd, A Mishra, KC Smith, R Kapur, S Maheswaran… - Iscience, 2022 - cell.com
Circulating tumor cells (CTCs) enter the vasculature from solid tumors and disseminate
widely to initiate metastases. Mining the metastatic-enriched molecular signatures of CTCs …

Recent advances in deformation-assisted microfluidic cell sorting technologies

J Sun, X Huang, J Chen, R Xiang, X Ke, S Lin, W Xuan… - Analyst, 2023 - pubs.rsc.org
Cell sorting is an essential prerequisite for cell research and has great value in life science
and clinical studies. Among the many microfluidic cell sorting technologies, label-free …

Highly focused high-frequency travelling surface acoustic waves (SAW) for rapid single-particle sorting

DJ Collins, A Neild, Y Ai - Lab on a Chip, 2016 - pubs.rsc.org
High-speed sorting is an essential process in a number of clinical and research applications,
where single cells, droplets and particles are segregated based on their properties in a …

Image-based cell sorting using focused travelling surface acoustic waves

AA Nawaz, D Soteriou, CK Xu, R Goswami, M Herbig… - Lab on a Chip, 2023 - pubs.rsc.org
Sorting cells is an essential primary step in many biological and clinical applications such as
high-throughput drug screening, cancer research and cell transplantation. Cell sorting …

Automated cell-type classification combining dilated convolutional neural networks with label-free acoustic sensing

HJ Jeon, HG Lim, KK Shung, OJ Lee, MG Kim - Scientific Reports, 2022 - nature.com
This study aimed to automatically classify live cells based on their cell type by analyzing the
patterns of backscattered signals of cells with minimal effect on normal cell physiology and …

Autofluorescence of NADH is a new biomarker for sorting and characterizing cancer stem cells in human glioma

Y Yuan, Z Yan, J Miao, R Cai, M Zhang, Y Wang… - Stem Cell Research & …, 2019 - Springer
Background The existing cell surface markers used for sorting glioma stem cells (GSCs)
have obvious limitations, such as vulnerability to the enzymatic digestion and time …

Multiscale Design of Cell‐Type–Specific Pharmacokinetic/Pharmacodynamic Models for Personalized Medicine: Application to Temozolomide in Brain Tumors

A Ballesta, Q Zhou, X Zhang, H Lv… - CPT: pharmacometrics …, 2014 - Wiley Online Library
Optimizing anticancer therapeutics needs to account for variable drug responses in
heterogeneous cell populations within the tumor as well as in organs of toxicity. To address …

High-throughput, multiparameter analysis of single cells

T Haselgrübler, M Haider, B Ji, K Juhasz… - Analytical and …, 2014 - Springer
Heterogeneity of cell populations in various biological systems has been widely recognized,
and the highly heterogeneous nature of cancer cells has been emerging with clinical …

Standardization of flow cytometry and cell sorting to enable a transcriptomic analysis in a multi-site sarcoidosis study

RE Magallon, LD Harmacek, NK Arger, P Grewal… - PloS one, 2023 - journals.plos.org
The contribution and regulation of various CD4+ T cell lineages that occur with remitting vs
progressive courses in sarcoidosis are poorly understood. We developed a multiparameter …

Multiple outcome particle manipulation using cascaded surface acoustic waves (CSAW)

JW Ng, A Neild - Microfluidics and Nanofluidics, 2021 - Springer
On-chip fluorescent activates cell sorting (FACS) requires the optical identification of a cell's
type followed by the selective displacement of that particle from the incoming streamline, the …