Therapeutic and Phytochemical Properties of Thymoquinone Derived from Nigella sativa

G Tiwari, M Gupta, LD Devhare… - Current Drug Research …, 2024 - benthamdirect.com
Background: Nigella sativa (N. sativa), commonly known as black seed or black cumin,
belongs to the family Ranunculaceae. It contains several phytoconstituents, Thymoquinone …

[HTML][HTML] Thymoquinone attenuates rheumatoid arthritis by downregulating TLR2, TLR4, TNF-α, IL-1, and NFκB expression levels

S Arjumand, M Shahzad, A Shabbir… - Biomedicine & …, 2019 - Elsevier
Background Thymoquinone (TQ), the most important active principle of Nigella sativa is
known to have anti-inflammatory, analgesic, antimicrobial and antioxidant properties. Aim …

Moringa rivae leaf extracts attenuate Complete Freund's adjuvant-induced arthritis in Wistar rats via modulation of inflammatory and oxidative stress biomarkers

A Saleem, M Saleem, MF Akhtar, M Shahzad… - …, 2020 - Springer
Moringa rivae is widely used as a traditional remedy against arthritis. The present research
was designed to evaluate the anti-arthritic potential of Moringa rivae extracts. Treatment of …

β-Sitosterol-loaded solid lipid nanoparticles ameliorate complete Freund's adjuvant-induced arthritis in rats: involvement of NF-кB and HO-1/Nrf-2 pathway

F Zhang, Z Liu, X He, Z Li, B Shi, F Cai - Drug delivery, 2020 - Taylor & Francis
Rheumatoid arthritis (RA), autoimmune disease that is categorized via chronic inflammation
manifestation, obesity, cardiovascular risk and even enhanced the mortality and affect the …

Ephedra gerardiana aqueous ethanolic extract and fractions attenuate Freund Complete Adjuvant induced arthritis in Sprague Dawley rats by downregulating PGE2 …

AM Uttra, M Shahzad, A Shabbir, S Jahan - Journal of …, 2018 - Elsevier
Ethnopharmacological relevance The whole plant, roots and stems of Ephedra gerardiana
(Family Ephedraceae) have long been used as a folk remedy to treat rheumatism and …

Nerolidol: a potential approach in rheumatoid arthritis through reduction of TNF-α, IL-1β, IL-6, NF-kB, COX-2 and antioxidant effect in CFA-induced arthritic model

S Akhter, HM Irfan, Alamgeer, S Jahan… - …, 2022 - Springer
Rheumatoid arthritis is primarily associated with inflammation and increased level of
proinflammatory cytokines which are released by immune cells, macrophages or activation …

Immunomodulatory and anti-inflammatory potential of curcumin for the treatment of allergic asthma: effects on expression levels of pro-inflammatory cytokines and …

H Shahid, M Shahzad, A Shabbir, G Saghir - Inflammation, 2019 - Springer
Curcumin is well known for possessing anti-inflammatory properties and for its beneficial
effects in the treatment of asthma. Current study investigates the immunomodulatory and anti …

[HTML][HTML] Ziziphora clinopodioides ameliorated rheumatoid arthritis and inflammatory paw edema in different models of acute and chronic inflammation

A Shabbir, SA Batool, MI Basheer, M Shahzad… - Biomedicine & …, 2018 - Elsevier
Ziziphora clinopodioides has been used in traditional medicine for its anti-inflammatory
properties. Current study is believed to first time report the potential of Z. clinopodioides …

Identification of Cyclic Sulfonamides with an N-Arylacetamide Group as α-Glucosidase and α-Amylase Inhibitors: Biological Evaluation and Molecular Modeling

FA Saddique, M Ahmad, UA Ashfaq, M Muddassar… - Pharmaceuticals, 2022 - mdpi.com
Diabetes mellitus (DM), a complicated metabolic disorder, is due to insensitivity to insulin
function or reduction in insulin secretion, which results in postprandial hyperglycemia. α …

Anti-Arthritic and Immunomodulatory Potential of Methanolic, n-Hexane, and Ethyl Acetate Fractions of Bark of Acacia modesta on Complete Freund's Adjuvant …

K Mashaal, A Shabbir, MA Khan, H Hameed… - Pharmaceutics, 2023 - mdpi.com
Rheumatoid arthritis is an autoimmune disorder and topic of interest for researchers due to
its increasing frequency and limited treatment. Acacia modesta Wall is known to treat …