Precisely controlled cell deformations are key to cell migration, division and tissue
morphogenesis, and have been implicated in cell differentiation during development, as well …

D'Arcy Thompson was a proponent of applying mathematical and physical principles to
biological systems, an approach that is becoming increasingly common in developmental …

The heterogeneity of small extracellular vesicles and presence of non-vesicular extracellular
matter have led to debate about contents and functional properties of exosomes. Here, we …

Microbial biochemicals have been indicated as the primary stimulators of innate immunity,
the first line of the body's defence against infections. However, the influence of topological …

Contractile actomyosin bundles, stress fibers, govern key cellular processes including
migration, adhesion, and mechanosensing. Stress fibers are thus critical for developmental …

The actin cortex is a thin layer of actin, myosin and actin-binding proteins that underlies the
membrane of most animal cells. It is highly dynamic and can undergo remodelling on …

Although myosin II filaments are known to exist in non-muscle cells,, their dynamics and
organization are incompletely understood. Here, we combined structured illumination …

Contractile actomyosin networks are responsible for the production of intracellular forces.
There is increasing evidence that bundles of actin filaments form interconnected and …

Epithelial tissues are defined by polarized epithelial cells that are integrated into tissues and
exhibit barrier function in order to regulate what is allowed to pass between cells. Cell-cell …

In animal cells, shape is mostly determined by the actomyosin cortex, a thin cytoskeletal
network underlying the plasma membrane. Myosin motors generate tension in the cortex …