Colistin Resistance in Acinetobacter baumannii: Molecular Mechanisms and Epidemiology

K Novović, B Jovčić - Antibiotics, 2023 - mdpi.com
Acinetobacter baumannii is recognized as a clinically significant pathogen causing a wide
spectrum of nosocomial infections. Colistin was considered a last-resort antibiotic for the …

Treatment of patients with serious infections due to carbapenem‐resistant Acinetobacter baumannii: How viable are the current options?

JN O'Donnell, V Putra, TP Lodise - … : The Journal of Human …, 2021 - Wiley Online Library
This review critically appraises the published microbiologic and clinical data on the
treatment of patients with carbapenem‐resistant Acinetobacter baumannii infections …

[HTML][HTML] Comparative genomics and molecular epidemiology of colistin-resistant Acinetobacter baumannii

J Kabic, K Novovic, D Kekic, A Trudic, N Opavski… - Computational and …, 2023 - Elsevier
This study aimed to investigate the prevalence and resistance mechanisms of colistin-
resistant Acinetobacter baumannii (ColRAB) isolates in Serbia, assess their genetic …

Acinetobacter baumannii: an evolving and cunning opponent

J Shi, J Cheng, S Liu, Y Zhu, M Zhu - Frontiers in Microbiology, 2024 - frontiersin.org
Acinetobacter baumannii is one of the most common multidrug-resistant pathogens causing
nosocomial infections. The prevalence of multidrug-resistant A. baumannii infections is …

Drug‑resistant Acinetobacter baumannii: From molecular mechanisms to potential therapeutics

HJ Wu, ZG Xiao, XJ Lv, HT Huang… - Experimental and …, 2023 - spandidos-publications.com
Bacterial drug resistance is increasingly becoming an important problem that needs to be
solved urgently in modern clinical practices. Infection caused by Acinetobacter baumannii is …

Retained colistin susceptibility in clinical Acinetobacter baumannii isolates with multiple mutations in pmrCAB and lpxACD operons

MM Zafer, AFA Hussein, MH Al-Agamy… - Frontiers in Cellular …, 2023 - frontiersin.org
The progressive increase in the resistance rates to first-and second-line antibiotics has
forced the reuse of colistin as last-line treatment for Acinetobacter baumannii infections, but …

Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii isolates reveals the emergence of blaOXA-23 and blaNDM-1 encoding international …

S Kumar, PP Patil, L Singhal, P Ray, PB Patil… - Infection, Genetics and …, 2019 - Elsevier
Acinetobacter baumannii is a nosocomial pathogen increasingly affecting the critically ill
patients and represents a major public health challenge. Carbapenem-resistant A …

An approach to measuring colistin plasma levels regarding the treatment of multidrug-resistant bacterial infection

T Pacheco, RH Bustos, D González, V Garzón… - Antibiotics, 2019 - mdpi.com
Antimicrobial resistance to antibiotic treatment has significantly increased during recent
years, causing this to become a worldwide public health problem. More than 70% of …

Colistin Resistance in Environmental Isolates of Acinetobacter baumannii

B Jovcic, K Novovic, S Dekic, J Hrenovic - Microbial drug resistance, 2021 - liebertpub.com
Although the molecular mechanisms of carbapenem resistance of environmental isolates of
Acinetobacter baumannii are well described, data on the mechanisms of colistin resistance …

Acinetobacter baumannii international clone 2 co-producing OXA-23, NDM-1, and ArmA emerging in South America

T Martins-Gonçalves, JS Pimenta… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Acinetobacter baumannii is a leading cause of healthcare-associated infections worldwide.
The clinical significance of A. baumannii lies in its ability to acquire multiple resistance …