Optimized Microscale Protein Aggregation Suppression Assay: A Method for Evaluating the Holdase Activity of Chaperones
Many molecular chaperones act as holdases by binding hydrophobic regions of substrates
to prevent aggregation. Therefore, measuring holdase activity is an amenable method to …
to prevent aggregation. Therefore, measuring holdase activity is an amenable method to …
Future Directions and Challenges in Enzyme Research for Neurodegenerative Diseases
KM Rathi, PV Pingat, SM Firdous - Enzymes in Neurodegenerative …, 2024 - Springer
Neurodegenerative diseases (NDs) pose a significant health challenge characterized by
progressive neuronal loss and cognitive decline. Despite extensive research, effective …
progressive neuronal loss and cognitive decline. Despite extensive research, effective …