Naringin, chemically 4′, 5, 7-trihydroxyflavanone-7-rhamnoglucoside, is a major flavanone
glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. It has been …

Parkinson's disease is a chronic, debilitating neurodegenerative movement disorder
characterized by progressive degeneration of dopaminergic neurons in the substantia nigra …

Well-established studies have shown an elevated level of reactive oxygen species (ROS)
that induces oxidative stress in the Alzheimer's disease (AD) patient's brain and an animal …

Chronic neuroinflammation is responsible for multiple neurodegenerative diseases, such as
Alzheimer's disease, Parkinson's disease, and Huntington's disease. Lipopolysaccharide …

Microglia plays a critical role in the brain and protects neuronal cells from toxins. However,
over-activation of microglia leads to deleterious effects. Lipopolysaccharide (LPS) has been …

Chronic exposure of a naturally occurring metal arsenic leads to renal and hepatic diseases.
Naringin, a flavanone glycoside, possesses anti-inflammatory and anti-oxidant potential …

Nuclear factor-erythroid 2-related factor-2 (Nrf2) mediated regulation of cellular antioxidant
production and the anti-inflammatory mechanism play an important role in neuroprotection …

Chronic, unhealed diabetic foot ulcer (DFU) is one of the most severe complications of
diabetes mellitus (DM). Naringin, a flavanone glycoside antioxidant, was reported to have …

Huntington's disease (HD), a neurodegenerative disease, normally starts in the prime of
adult life, followed by a gradual occurrence of characteristic psychiatric disturbances and …

Parkinson's disease (PD) is a neurodegenerative disease that is accompanied with the loss
of dopaminergic neurons in the substantia nigra pars compacta which subsequently leads to …