[HTML][HTML] Combination strategies to augment immune check point inhibitors efficacy-implications for translational research
H Varayathu, V Sarathy, BE Thomas, SS Mufti… - Frontiers in …, 2021 - frontiersin.org
Immune checkpoint inhibitor therapy has revolutionized the field of cancer immunotherapy.
Even though it has shown a durable response in some solid tumors, several patients do not …
Even though it has shown a durable response in some solid tumors, several patients do not …
Metformin as a booster of cancer immunotherapy
J Panaampon, Y Zhou, C Saengboonmee - International …, 2023 - Elsevier
Metformin, a biguanide antidiabetic, has been studied for its repurposing effects in oncology.
Although a modest effect was observed in a single-agent regimen, metformin can synergize …
Although a modest effect was observed in a single-agent regimen, metformin can synergize …
[HTML][HTML] Overcoming resistance to immune checkpoint inhibitors in head and neck squamous cell carcinomas
LV Dos Santos, CM Abrahão, WN William Jr - Frontiers in oncology, 2021 - frontiersin.org
Preclinical data suggest that head and neck squamous cell carcinomas (HNSCC) may
evade immune surveillance and induce immunosuppression. One mechanism of immune …
evade immune surveillance and induce immunosuppression. One mechanism of immune …