Through their specific interactions with proteins, cellular glycans play key roles in a wide
range of physiological and pathological processes. One of the main goals of research in the …

A major branch of glycobiology and glycan-focused biomedicine studies the interaction
between carbohydrates and other biopolymers, most importantly, glycan-binding proteins …

Fetal syncytiotrophoblasts form a unique fused multinuclear surface that is bathed in
maternal blood, and constitutes the main interface between fetus and mother …

Highlights•Examining pathogen lectins for binding specificity and selective inhibition.•
Understanding host defense: fine specificity study of innate immune receptors.•Anti-glycan …

Malaria caused by Plasmodium falciparum results in over 400,000 deaths annually,
predominantly affecting African children. In addition, non-falciparum species including vivax …

Infections with the human malaria parasite Plasmodium falciparum during pregnancy can
lead to severe complications for both mother and child, resulting from the cytoadhesion of …

Background: Preterm birth (PTB) is a major cause of infant morbidity and mortality in
developing countries. Recent data suggest that in addition to Human Immunodeficiency …

Of all the outcomes of Plasmodium falciparum infection, the coma of cerebral malaria (CM) is
particularly deadly. Malariologists have long wondered how some patients develop this …

Malaria causes tremendous early childhood morbidity and mortality, providing an urgent
impetus for the development of a vaccine that is effective in neonates. However, the infant …

Plasmodium parasites cause malaria disease, one of the leading global health burdens for
humanity, infecting hundreds of millions of people each year. Different glycans on the …